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Fabrication and Applications of Microfluidic Devices: A Review
Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921936/ https://www.ncbi.nlm.nih.gov/pubmed/33670545 http://dx.doi.org/10.3390/ijms22042011 |
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author | Niculescu, Adelina-Gabriela Chircov, Cristina Bîrcă, Alexandra Cătălina Grumezescu, Alexandru Mihai |
author_facet | Niculescu, Adelina-Gabriela Chircov, Cristina Bîrcă, Alexandra Cătălina Grumezescu, Alexandru Mihai |
author_sort | Niculescu, Adelina-Gabriela |
collection | PubMed |
description | Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices. |
format | Online Article Text |
id | pubmed-7921936 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79219362021-03-03 Fabrication and Applications of Microfluidic Devices: A Review Niculescu, Adelina-Gabriela Chircov, Cristina Bîrcă, Alexandra Cătălina Grumezescu, Alexandru Mihai Int J Mol Sci Review Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices. MDPI 2021-02-18 /pmc/articles/PMC7921936/ /pubmed/33670545 http://dx.doi.org/10.3390/ijms22042011 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Niculescu, Adelina-Gabriela Chircov, Cristina Bîrcă, Alexandra Cătălina Grumezescu, Alexandru Mihai Fabrication and Applications of Microfluidic Devices: A Review |
title | Fabrication and Applications of Microfluidic Devices: A Review |
title_full | Fabrication and Applications of Microfluidic Devices: A Review |
title_fullStr | Fabrication and Applications of Microfluidic Devices: A Review |
title_full_unstemmed | Fabrication and Applications of Microfluidic Devices: A Review |
title_short | Fabrication and Applications of Microfluidic Devices: A Review |
title_sort | fabrication and applications of microfluidic devices: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921936/ https://www.ncbi.nlm.nih.gov/pubmed/33670545 http://dx.doi.org/10.3390/ijms22042011 |
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