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Fabrication and Applications of Microfluidic Devices: A Review

Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse re...

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Detalles Bibliográficos
Autores principales: Niculescu, Adelina-Gabriela, Chircov, Cristina, Bîrcă, Alexandra Cătălina, Grumezescu, Alexandru Mihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921936/
https://www.ncbi.nlm.nih.gov/pubmed/33670545
http://dx.doi.org/10.3390/ijms22042011
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author Niculescu, Adelina-Gabriela
Chircov, Cristina
Bîrcă, Alexandra Cătălina
Grumezescu, Alexandru Mihai
author_facet Niculescu, Adelina-Gabriela
Chircov, Cristina
Bîrcă, Alexandra Cătălina
Grumezescu, Alexandru Mihai
author_sort Niculescu, Adelina-Gabriela
collection PubMed
description Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices.
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spelling pubmed-79219362021-03-03 Fabrication and Applications of Microfluidic Devices: A Review Niculescu, Adelina-Gabriela Chircov, Cristina Bîrcă, Alexandra Cătălina Grumezescu, Alexandru Mihai Int J Mol Sci Review Microfluidics is a relatively newly emerged field based on the combined principles of physics, chemistry, biology, fluid dynamics, microelectronics, and material science. Various materials can be processed into miniaturized chips containing channels and chambers in the microscale range. A diverse repertoire of methods can be chosen to manufacture such platforms of desired size, shape, and geometry. Whether they are used alone or in combination with other devices, microfluidic chips can be employed in nanoparticle preparation, drug encapsulation, delivery, and targeting, cell analysis, diagnosis, and cell culture. This paper presents microfluidic technology in terms of the available platform materials and fabrication techniques, also focusing on the biomedical applications of these remarkable devices. MDPI 2021-02-18 /pmc/articles/PMC7921936/ /pubmed/33670545 http://dx.doi.org/10.3390/ijms22042011 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Niculescu, Adelina-Gabriela
Chircov, Cristina
Bîrcă, Alexandra Cătălina
Grumezescu, Alexandru Mihai
Fabrication and Applications of Microfluidic Devices: A Review
title Fabrication and Applications of Microfluidic Devices: A Review
title_full Fabrication and Applications of Microfluidic Devices: A Review
title_fullStr Fabrication and Applications of Microfluidic Devices: A Review
title_full_unstemmed Fabrication and Applications of Microfluidic Devices: A Review
title_short Fabrication and Applications of Microfluidic Devices: A Review
title_sort fabrication and applications of microfluidic devices: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921936/
https://www.ncbi.nlm.nih.gov/pubmed/33670545
http://dx.doi.org/10.3390/ijms22042011
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