The FDA-Approved Antiviral Raltegravir Inhibits Fascin1-Dependent Invasion of Colorectal Tumor Cells In Vitro and In Vivo

SIMPLE SUMMARY: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. Serrated adenocarcinoma (SAC) has been recently recognized by the WHO as a histological CRC with bad prognosis. Consistent with previous evidence, our group identified Fascin1 as a protein directly...

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Detalles Bibliográficos
Autores principales: Alburquerque-González, Begoña, Bernabé-García, Ángel, Bernabé-García, Manuel, Ruiz-Sanz, Javier, López-Calderón, Fernando Feliciano, Gonnelli, Leonardo, Banci, Lucia, Peña-García, Jorge, Luque, Irene, Nicolás, Francisco José, Cayuela-Fuentes, María Luisa, Luchinat, Enrico, Pérez-Sánchez, Horacio, Montoro-García, Silvia, Conesa-Zamora, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921938/
https://www.ncbi.nlm.nih.gov/pubmed/33670655
http://dx.doi.org/10.3390/cancers13040861

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