A LAT-Based Signaling Complex in the Immunological Synapse as Determined with Live Cell Imaging Is Less Stable in T Cells with Regulatory Capability

Peripheral immune regulation is critical for the maintenance of self-tolerance. Here we have investigated signaling processes that distinguish T cells with regulatory capability from effector T cells. The murine Tg4 T cell receptor recognizes a peptide derived from the self-antigen myelin basic prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yikui, Tunbridge, Helen M., Britton, Graham J., Hill, Elaine V., Sinai, Parisa, Cirillo, Silvia, Thompson, Clare, Fallah-Arani, Farnaz, Dovedi, Simon J., Wraith, David C., Wülfing, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921939/
https://www.ncbi.nlm.nih.gov/pubmed/33671236
http://dx.doi.org/10.3390/cells10020418

Ejemplares similares

Ejemplares similares