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Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort

According to the evidence demonstrating vaccines’ safety and effectiveness in anticipation of and during pregnancy, several countries have established immunization programs during the periconceptional period. Here, we evaluated vaccination status among 220 mother–child pairs, using data from the ‘Ma...

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Autores principales: Barchitta, Martina, Maugeri, Andrea, Magnano San Lio, Roberta, La Rosa, Maria Clara, La Mastra, Claudia, Favara, Giuliana, Giunta, Giuliana, Cianci, Antonio, Agodi, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921954/
https://www.ncbi.nlm.nih.gov/pubmed/33671412
http://dx.doi.org/10.3390/vaccines9020168
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author Barchitta, Martina
Maugeri, Andrea
Magnano San Lio, Roberta
La Rosa, Maria Clara
La Mastra, Claudia
Favara, Giuliana
Giunta, Giuliana
Cianci, Antonio
Agodi, Antonella
author_facet Barchitta, Martina
Maugeri, Andrea
Magnano San Lio, Roberta
La Rosa, Maria Clara
La Mastra, Claudia
Favara, Giuliana
Giunta, Giuliana
Cianci, Antonio
Agodi, Antonella
author_sort Barchitta, Martina
collection PubMed
description According to the evidence demonstrating vaccines’ safety and effectiveness in anticipation of and during pregnancy, several countries have established immunization programs during the periconceptional period. Here, we evaluated vaccination status among 220 mother–child pairs, using data from the ‘Mamma & Bambino’ cohort. The self-reported data were evaluated at delivery, and with planned follow-ups at 1–2 years after delivery. In general, we noted that the vaccination status among the women was heterogeneous, ranging from 8.3% (vaccine against Human Papillomavirus, HPV) to 65.6% (vaccine against Diphtheria Tetanus and Pertussis, DTaP). Excluding the women who contracted the diseases in the past, the main ground for refusal was the lack of information. We also demonstrated that increasing age was associated with higher odds of not being vaccinated against Measles-Mumps-Rubella (MMR; OR = 1.12; 95% CI = 1.04–1.21; p = 0.004), HPV (OR = 1.20; 95% CI = 1.08–1.33; p = 0.001) and DTaP (OR =1.09; 95% CI = 1.01–1.18; p = 0.040). As expected, we showed that the proportion of newborns vaccinated with the Hexavalent and Pneumococcal vaccines was high (99.5% and 98.6%, respectively), while the vaccination coverage against MMRV did not reach the auspicated threshold (84.1%). Overall, these results underlined the need for the improvement of women’s knowledge about the recommendations for vaccination, especially during pregnancy.
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spelling pubmed-79219542021-03-03 Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort Barchitta, Martina Maugeri, Andrea Magnano San Lio, Roberta La Rosa, Maria Clara La Mastra, Claudia Favara, Giuliana Giunta, Giuliana Cianci, Antonio Agodi, Antonella Vaccines (Basel) Article According to the evidence demonstrating vaccines’ safety and effectiveness in anticipation of and during pregnancy, several countries have established immunization programs during the periconceptional period. Here, we evaluated vaccination status among 220 mother–child pairs, using data from the ‘Mamma & Bambino’ cohort. The self-reported data were evaluated at delivery, and with planned follow-ups at 1–2 years after delivery. In general, we noted that the vaccination status among the women was heterogeneous, ranging from 8.3% (vaccine against Human Papillomavirus, HPV) to 65.6% (vaccine against Diphtheria Tetanus and Pertussis, DTaP). Excluding the women who contracted the diseases in the past, the main ground for refusal was the lack of information. We also demonstrated that increasing age was associated with higher odds of not being vaccinated against Measles-Mumps-Rubella (MMR; OR = 1.12; 95% CI = 1.04–1.21; p = 0.004), HPV (OR = 1.20; 95% CI = 1.08–1.33; p = 0.001) and DTaP (OR =1.09; 95% CI = 1.01–1.18; p = 0.040). As expected, we showed that the proportion of newborns vaccinated with the Hexavalent and Pneumococcal vaccines was high (99.5% and 98.6%, respectively), while the vaccination coverage against MMRV did not reach the auspicated threshold (84.1%). Overall, these results underlined the need for the improvement of women’s knowledge about the recommendations for vaccination, especially during pregnancy. MDPI 2021-02-17 /pmc/articles/PMC7921954/ /pubmed/33671412 http://dx.doi.org/10.3390/vaccines9020168 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Barchitta, Martina
Maugeri, Andrea
Magnano San Lio, Roberta
La Rosa, Maria Clara
La Mastra, Claudia
Favara, Giuliana
Giunta, Giuliana
Cianci, Antonio
Agodi, Antonella
Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort
title Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort
title_full Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort
title_fullStr Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort
title_full_unstemmed Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort
title_short Vaccination Status of Mothers and Children from the ‘Mamma & Bambino’ Cohort
title_sort vaccination status of mothers and children from the ‘mamma & bambino’ cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921954/
https://www.ncbi.nlm.nih.gov/pubmed/33671412
http://dx.doi.org/10.3390/vaccines9020168
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