Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics

To define the growing significance of cellular targets and/or effectors of cancer drugs, we examined the fitness dependency of cellular targets and effectors of cancer drug targets across human cancer cells from 19 cancer types. We observed that the deletion of 35 out of 47 cellular effectors and/or...

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Detalles Bibliográficos
Autores principales: George, Bijesh, Pillai, P. Mukundan, Paul, Aswathy Mary, Amjesh, Revikumar, Leitzel, Kim, Ali, Suhail M., Sandiford, Oleta, Lipton, Allan, Rameshwar, Pranela, Hortobagyi, Gabriel N., Pillai, Madhavan Radhakrishna, Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7921985/
https://www.ncbi.nlm.nih.gov/pubmed/33670680
http://dx.doi.org/10.3390/cells10020433

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