Cargando…

Costunolide, a Sesquiterpene Lactone, Suppresses Skin Cancer via Induction of Apoptosis and Blockage of Cell Proliferation

Costunolide is a naturally occurring sesquiterpene lactone that demonstrates various therapeutic actions such as anti-oxidative, anti-inflammatory, and anti-cancer properties. Costunolide has recently emerged as a potential anti-cancer agent in various types of cancer, including colon, lung, and bre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Sung Ho, Cho, Young-Chang, Lim, Jae Sung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922093/ https://www.ncbi.nlm.nih.gov/pubmed/33669832 http://dx.doi.org/10.3390/ijms22042075

Ejemplares similares

Costunolide—A Bioactive Sesquiterpene Lactone with Diverse Therapeutic Potential
por: Kim, Dae Yong, et al.
Publicado: (2019)

Inhibition of Inflammatory and Proliferative Responses of Human Keratinocytes Exposed to the Sesquiterpene Lactones Dehydrocostuslactone and Costunolide
por: Scarponi, Claudia, et al.
Publicado: (2014)

Amelioration of Benign Prostatic Hyperplasia by Costunolide and Dehydrocostus Lactone in Wistar Rats
por: Choi, Dohyun, et al.
Publicado: (2021)

Dynamics of germination stimulants dehydrocostus lactone and costunolide in the root exudates and extracts of sunflower
por: Wu, Wenlong, et al.
Publicado: (2022)

Dehydrobrachylaenolide: an eudesmane-type sesquiterpene lactone
por: Rademeyer, M., et al.
Publicado: (2008)

Biosynthesis of Sesquiterpene Lactones in Pyrethrum (Tanacetum cinerariifolium)
por: Ramirez, Aldana M., et al.
Publicado: (2013)

Guaianolide Sesquiterpene Lactones from Centaurothamnus maximus
por: Hussien, Taha A., et al.
Publicado: (2021)

Anti-Inflammatory and Immunoregulatory Action of Sesquiterpene Lactones
por: Paço, Ana, et al.
Publicado: (2022)

Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo
por: Huang, Hai, et al.
Publicado: (2021)

The Sesquiterpene Lactone Dehydroleucodine Triggers Senescence and Apoptosis in Association with Accumulation of DNA Damage Markers
por: Costantino, Valeria V., et al.
Publicado: (2013)

Antineoplastic Properties by Proapoptotic Mechanisms Induction of Inula viscosa and Its Sesquiterpene Lactones Tomentosin and Inuviscolide
por: Migheli, Rossana, et al.
Publicado: (2022)

Induction of Apoptosis by Costunolide in Bladder Cancer Cells is Mediated through ROS Generation and Mitochondrial Dysfunction
por: Rasul, Azhar, et al.
Publicado: (2013)

NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death
por: Lim, Chuan Bian, et al.
Publicado: (2012)

Aromaticine, a sesquiterpene lactone from Amblyopappus pusillus
por: Brito, Iván, et al.
Publicado: (2008)

Dehydroleucodin: a guaiane-type sesquiterpene lactone
por: Priestap, Horacio A., et al.
Publicado: (2011)

Cynaratriol, a sesquiterpene lactone from Centaurea musimomum
por: López-Rodríguez, Matías, et al.
Publicado: (2009)

Cytotoxic Sesquiterpene Lactones from Kauna lasiophthalma Griseb
por: Maldonado, Eliana M., et al.
Publicado: (2014)

Hologram QSAR Studies of Antiprotozoal Activities of Sesquiterpene Lactones
por: Trossini, Gustavo H. G., et al.
Publicado: (2014)

Quantitative Structure − Antiprotozoal Activity Relationships of Sesquiterpene Lactones (†)
por: Schmidt, Thomas J., et al.
Publicado: (2009)

BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide
por: Škorpilová, Ludmila, et al.
Publicado: (2017)

Are sesquiterpene lactones the elusive KARRIKIN-INSENSITIVE2 ligand?
por: Rahimi, Mehran, et al.
Publicado: (2021)

Sesquiterpene Lactones: Promising Natural Compounds to Fight Inflammation
por: Matos, Melanie S., et al.
Publicado: (2021)

Dermal Absorption of Sesquiterpene Lactones from Arnica Tincture
por: Jürgens, Franziska M., et al.
Publicado: (2022)

Antifungal Activity of the Sesquiterpene Lactones from Psephellus bellus
por: Nawrot, Joanna, et al.
Publicado: (2021)

Localization of Sesquiterpene Lactones Biosynthesis in Flowers of Arnica Taxa
por: Parafiniuk, Agata, et al.
Publicado: (2023)

Microbial Transformation of the Sesquiterpene Lactone, Vulgarin, by Aspergillus niger
por: ElGamal, Reem A., et al.
Publicado: (2023)

Effects of Sesquiterpene Lactones on Primary Cilia Formation (Ciliogenesis)
por: Murillo-Pineda, Marina, et al.
Publicado: (2023)

Costunolide Induces Apoptosis via the Reactive Oxygen Species and Protein Kinase B Pathway in Oral Cancer Cells
por: Huang, Hai, et al.
Publicado: (2021)

Enhanced cytostatic activity of the sesquiterpene lactone eupatoriopicrin by glutathione depletion.
por: Woerdenbag, H. J., et al.
Publicado: (1989)

In Vitro Antiplasmodial Activity of Sesquiterpene Lactones from Ambrosia tenuifolia
por: Sülsen, V., et al.
Publicado: (2011)

Natural Sesquiterpene Lactones Induce Oxidative Stress in Leishmania mexicana
por: Barrera, Patricia, et al.
Publicado: (2013)

Preparation of Sesquiterpene Lactone Derivatives: Cytotoxic Activity and Selectivity of Action
por: Beer, María F., et al.
Publicado: (2019)

Estimation of Costunolide and Dehydrocostus Lactone in Saussurea lappa and its Polyherbal Formulations followed by their Stability Studies Using HPLC-DAD
por: Rao Vadaparthi, P.R., et al.
Publicado: (2015)

Naturally Isolated Sesquiterpene Lactone and Hydroxyanthraquinone Induce Apoptosis in Oral Squamous Cell Carcinoma Cell Line
por: Shams, Afshan, et al.
Publicado: (2023)

The Sesquiterpene Lactone Cynaropicrin Manifests Strong Cytotoxicity in Glioblastoma Cells U-87 MG by Induction of Oxidative Stress
por: Rotondo, Rossella, et al.
Publicado: (2022)

Eucannabinolide, a novel sesquiterpene lactone, suppresses the growth, metastasis and BCSCS-like traits of TNBC via inactivation of STAT3
por: Zhu, Zhihui, et al.
Publicado: (2020)

Sesquiterpene Lactones Isolated from Elephantopus scaber L. Inhibits Human Lymphocyte Proliferation and the Growth of Tumour Cell Lines and Induces Apoptosis In Vitro
por: Geetha, B. S., et al.
Publicado: (2012)

Induction of G(2)/M arrest and apoptosis through mitochondria pathway by a dimer sesquiterpene lactone from Smallanthus sonchifolius in HeLa cells
por: Kitai, Yurika, et al.
Publicado: (2016)

Artemisia annua L.: evidence of sesquiterpene lactones’ fraction antinociceptive activity
por: de Faveri Favero, Fabricio, et al.
Publicado: (2014)

Acetyl and butyryl cholinesterase inhibitory sesquiterpene lactones from Amberboa ramosa
por: Ibrahim, Muhammad, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7b9uke8pcj0nnq13jg4jud23at