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The MHC Class-I Transactivator NLRC5: Implications to Cancer Immunology and Potential Applications to Cancer Immunotherapy

The immune system constantly monitors the emergence of cancerous cells and eliminates them. CD8(+) cytotoxic T lymphocytes (CTLs), which kill tumor cells and provide antitumor immunity, select their targets by recognizing tumor antigenic peptides presented by MHC class-I (MHC-I) molecules. Cancer ce...

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Detalles Bibliográficos
Autores principales:	Shukla, Akhil, Cloutier, Maryse, Appiya Santharam, Madanraj, Ramanathan, Sheela, Ilangumaran, Subburaj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922096/ https://www.ncbi.nlm.nih.gov/pubmed/33671123 http://dx.doi.org/10.3390/ijms22041964

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