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Creatine Supplementation in Children and Adolescents

Creatine is a popular ergogenic aid among athletic populations with consistent evidence indicating that creatine supplementation also continues to be commonly used among adolescent populations. In addition, the evidence base supporting the therapeutic benefits of creatine supplementation for a pleth...

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Autores principales: Jagim, Andrew R., Kerksick, Chad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922146/
https://www.ncbi.nlm.nih.gov/pubmed/33670822
http://dx.doi.org/10.3390/nu13020664
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author Jagim, Andrew R.
Kerksick, Chad M.
author_facet Jagim, Andrew R.
Kerksick, Chad M.
author_sort Jagim, Andrew R.
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description Creatine is a popular ergogenic aid among athletic populations with consistent evidence indicating that creatine supplementation also continues to be commonly used among adolescent populations. In addition, the evidence base supporting the therapeutic benefits of creatine supplementation for a plethora of clinical applications in both adults and children continues to grow. Among pediatric populations, a strong rationale exists for creatine to afford therapeutic benefits pertaining to multiple neuromuscular and metabolic disorders, with preliminary evidence for other subsets of clinical populations as well. Despite the strong evidence supporting the efficacy and safety of creatine supplementation among adult populations, less is known as to whether similar physiological benefits extend to children and adolescent populations, and in particular those adolescent populations who are regularly participating in high-intensity exercise training. While limited in scope, studies involving creatine supplementation and exercise performance in adolescent athletes generally report improvements in several ergogenic outcomes with limited evidence of ergolytic properties and consistent reports indicating no adverse events associated with supplementation. The purpose of this article is to summarize the rationale, prevalence of use, performance benefits, clinical applications, and safety of creatine use in children and adolescents.
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spelling pubmed-79221462021-03-03 Creatine Supplementation in Children and Adolescents Jagim, Andrew R. Kerksick, Chad M. Nutrients Review Creatine is a popular ergogenic aid among athletic populations with consistent evidence indicating that creatine supplementation also continues to be commonly used among adolescent populations. In addition, the evidence base supporting the therapeutic benefits of creatine supplementation for a plethora of clinical applications in both adults and children continues to grow. Among pediatric populations, a strong rationale exists for creatine to afford therapeutic benefits pertaining to multiple neuromuscular and metabolic disorders, with preliminary evidence for other subsets of clinical populations as well. Despite the strong evidence supporting the efficacy and safety of creatine supplementation among adult populations, less is known as to whether similar physiological benefits extend to children and adolescent populations, and in particular those adolescent populations who are regularly participating in high-intensity exercise training. While limited in scope, studies involving creatine supplementation and exercise performance in adolescent athletes generally report improvements in several ergogenic outcomes with limited evidence of ergolytic properties and consistent reports indicating no adverse events associated with supplementation. The purpose of this article is to summarize the rationale, prevalence of use, performance benefits, clinical applications, and safety of creatine use in children and adolescents. MDPI 2021-02-18 /pmc/articles/PMC7922146/ /pubmed/33670822 http://dx.doi.org/10.3390/nu13020664 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jagim, Andrew R.
Kerksick, Chad M.
Creatine Supplementation in Children and Adolescents
title Creatine Supplementation in Children and Adolescents
title_full Creatine Supplementation in Children and Adolescents
title_fullStr Creatine Supplementation in Children and Adolescents
title_full_unstemmed Creatine Supplementation in Children and Adolescents
title_short Creatine Supplementation in Children and Adolescents
title_sort creatine supplementation in children and adolescents
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922146/
https://www.ncbi.nlm.nih.gov/pubmed/33670822
http://dx.doi.org/10.3390/nu13020664
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