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RNA-Seq Analysis Reveals CCR5 as a Key Target for CRISPR Gene Editing to Regulate In Vivo NK Cell Trafficking

SIMPLE SUMMARY: Adoptive immunotherapy utilizing ex vivo expanded natural killer (NK) cells is being explored in the clinical and preclinical settings to treat hematological tumors. Previous work has shown that a large fraction of ex vivo expanded NK cells traffic into the liver following i.v. infus...

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Detalles Bibliográficos
Autores principales:	Levy, Emily R., Clara, Joseph A., Reger, Robert N., Allan, David S. J., Childs, Richard W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922167/ https://www.ncbi.nlm.nih.gov/pubmed/33669611 http://dx.doi.org/10.3390/cancers13040872

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