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Comparison of Huggins Coefficients and Osmotic Second Virial Coefficients of Buffered Solutions of Monoclonal Antibodies

The Huggins coefficient k(H) is a well-known metric for quantifying the increase in solution viscosity arising from intermolecular interactions in relatively dilute macromolecular solutions, and there has been much interest in this solution property in connection with developing improved antibody th...

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Detalles Bibliográficos
Autores principales: Pathak, Jai A., Nugent, Sean, Bender, Michael F., Roberts, Christopher J., Curtis, Robin J., Douglas, Jack F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922252/
https://www.ncbi.nlm.nih.gov/pubmed/33671342
http://dx.doi.org/10.3390/polym13040601

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