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Development of BCR-ABL1 Transgenic Zebrafish Model Reproducing Chronic Myeloid Leukemia (CML) Like-Disease and Providing a New Insight into CML Mechanisms
Zebrafish has proven to be a versatile and reliable experimental in vivo tool to study human hematopoiesis and model hematological malignancies. Transgenic technologies enable the generation of specific leukemia types by the expression of human oncogenes under specific promoters. Using this technolo...
Autores principales: | Zizioli, Daniela, Bernardi, Simona, Varinelli, Marco, Farina, Mirko, Mignani, Luca, Bosio, Katia, Finazzi, Dario, Monti, Eugenio, Polverelli, Nicola, Malagola, Michele, Borsani, Elisa, Borsani, Giuseppe, Russo, Domenico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922348/ https://www.ncbi.nlm.nih.gov/pubmed/33669758 http://dx.doi.org/10.3390/cells10020445 |
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