Cargando…

Activation of Apoptosis in a βB1-CTGF Transgenic Mouse Model

To reveal the pathomechanisms of glaucoma, a common cause of blindness, suitable animal models are needed. As previously shown, retinal ganglion cell and optic nerve degeneration occur in βB1-CTGF mice. Here, we aimed to determine possible apoptotic mechanisms and degeneration of different retinal c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Weiss, Maximilian, Reinehr, Sabrina, Mueller-Buehl, Ana M., Doerner, Johanna D., Fuchshofer, Rudolf, Stute, Gesa, Dick, H. Burkhard, Joachim, Stephanie C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922353/ https://www.ncbi.nlm.nih.gov/pubmed/33671472 http://dx.doi.org/10.3390/ijms22041997

Ejemplares similares

Cytokine and Complement Response in the Glaucomatous βB1-CTGF Mouse Model
por: Reinehr, Sabrina, et al.
Publicado: (2021)

Apoptotic retinal ganglion cell loss is accompanied by complement and cytokine response in the βB1-CTGF primary open-angle glaucoma mouse model
por: Mueller-Buehl, Ana Maria, et al.
Publicado: (2022)

Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma
por: Reinehr, Sabrina, et al.
Publicado: (2019)

CCN2/CTGF promotor activity in the developing and adult mouse eye
por: Dillinger, Andrea E., et al.
Publicado: (2021)

Synapse and Receptor Alterations in Two Different S100B-Induced Glaucoma-Like Models
por: Benning, Lara, et al.
Publicado: (2020)

Enhanced glaucomatous damage accompanied by glial response in a new multifactorial mouse model
por: Reinehr, Sabrina, et al.
Publicado: (2023)

S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model
por: Reinehr, Sabrina, et al.
Publicado: (2018)

Early remodelling of the extracellular matrix proteins tenascin‐C and phosphacan in retina and optic nerve of an experimental autoimmune glaucoma model
por: Reinehr, Sabrina, et al.
Publicado: (2016)

Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Microglia Activation in Retinal Ischemia Triggers Cytokine and Toll-Like Receptor Response
por: Wagner, Natalie, et al.
Publicado: (2020)

CCN2/CTGF tip the balance of growth factors towards TGF-β2 in primary open-angle glaucoma
por: Dillinger, Andrea E., et al.
Publicado: (2023)

Protective effects on the retina after ranibizumab treatment in an ischemia model
por: Joachim, Stephanie C., et al.
Publicado: (2017)

CTGF is overexpressed in malignant melanoma and promotes cell invasion and migration
por: Braig, S, et al.
Publicado: (2011)

Laquinimod protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model
por: Wilmes, Anna T., et al.
Publicado: (2018)

Comparable effects on tear film parameters after femtosecond laser-assisted and conventional cataract surgery
por: Schargus, Marc, et al.
Publicado: (2020)

CCN2/CTGF—A Modulator of the Optic Nerve Head Astrocyte
por: Dillinger, Andrea E., et al.
Publicado: (2022)

Fewer Functional Deficits and Reduced Cell Death after Ranibizumab Treatment in a Retinal Ischemia Model
por: Palmhof, Marina, et al.
Publicado: (2018)

HSP27 induced glaucomatous damage in mice of young and advanced age
por: Erb, Clivia, et al.
Publicado: (2023)

Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture
por: Tsai, Teresa, et al.
Publicado: (2020)

Correction to: Protective effect of the extremolytes ectoine and hydroxyectoine in a porcine organ culture
por: Tsai, Teresa, et al.
Publicado: (2021)

Anti-inflammatory cytokine and angiogenic factors levels in vitreous samples of diabetic retinopathy patients
por: Tsai, Teresa, et al.
Publicado: (2018)

Ischemic injury leads to extracellular matrix alterations in retina and optic nerve
por: Reinhard, Jacqueline, et al.
Publicado: (2017)

From Ganglion Cell to Photoreceptor Layer: Timeline of Deterioration in a Rat Ischemia/Reperfusion Model
por: Palmhof, Marina, et al.
Publicado: (2019)

Optic Nerve Degeneration after Retinal Ischemia/Reperfusion in a Rodent Model
por: Renner, Marina, et al.
Publicado: (2017)

Progressive Retinal and Optic Nerve Damage in a Mouse Model of Spontaneous Opticospinal Encephalomyelitis
por: Petrikowski, Laura, et al.
Publicado: (2022)

Correction to: Preservation of optic nerve structure by complement inhibition in experimental glaucoma
por: Gassel, Caroline J., et al.
Publicado: (2021)

Preservation of optic nerve structure by complement inhibition in experimental glaucoma
por: Gassel, Caroline J., et al.
Publicado: (2020)

Hypoxic Processes Induce Complement Activation via Classical Pathway in Porcine Neuroretinas
por: Mueller-Buehl, Ana M., et al.
Publicado: (2021)

Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response
por: Grotegut, Pia, et al.
Publicado: (2021)

Simultaneous Complement Response via Lectin Pathway in Retina and Optic Nerve in an Experimental Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2016)

Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals
por: Brigstock, David R.
Publicado: (2009)

Novel Porcine Retina Cultivation Techniques Provide Improved Photoreceptor Preservation
por: Wagner, Natalie, et al.
Publicado: (2020)

CTGF in kidney fibrosis and glomerulonephritis
por: Toda, Naohiro, et al.
Publicado: (2018)

Transfer of the Experimental Autoimmune Glaucoma Model from Rats to Mice—New Options to Study Glaucoma Disease
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Correlation of CTGF gene promoter methylation with CTGF expression in type 2 diabetes mellitus with or without nephropathy
por: ZHANG, HAO, et al.
Publicado: (2014)

CTGF siRNA ameliorates tubular cell apoptosis and tubulointerstitial fibrosis in obstructed mouse kidneys in a Sirt1-independent manner
por: Ren, Yunzhuo, et al.
Publicado: (2015)

The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes
por: Dendooven, Amélie, et al.
Publicado: (2011)

Increased Levels of Phosphorylated ERK Induce CTGF Expression in Autophagy-Deficient Mouse Hepatocytes
por: Seo, Hye-Young, et al.
Publicado: (2022)

Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model
por: Wiemann, Susanne, et al.
Publicado: (2020)

Proteomic Analysis of Retinal Tissue in an S100B Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_n3r34tfjodlkj9pluhr2sbss84