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Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma
Osteosarcoma (OS) is a rare malignant primary tumor of mesenchymal origin affecting bone. It is characterized by a complex genotype, mainly due to the high frequency of chromothripsis, which leads to multiple somatic copy number alterations and structural rearrangements. Any effort to design genome-...
Autores principales: | Landuzzi, Lorena, Manara, Maria Cristina, Lollini, Pier-Luigi, Scotlandi, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922432/ https://www.ncbi.nlm.nih.gov/pubmed/33671173 http://dx.doi.org/10.3390/cells10020416 |
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