Presepsin: A Promising Biomarker for Sepsis

Sepsis is the most common cause of mortality in non-cardiac ICUs. The quest for early diagnosis and treatment has led to the discovery of many biomarkers. In this issue, Abdelshafey et al. have evaluated presepsin, a novel biomarker for early detection of sepsis. Presepsin is formed by cleavage of N-terminal of soluble CD14 (sCD14) which is a member of the Toll-like receptors (TLRs). Studies have found a higher level of presepsin in septic patients and values above 946 ng/L correlated well with gram-negative bacterial sepsis. How to cite this article: Azim A. Presepsin: A Promising Biomarker for Sepsis. Indian J Crit Care Med 2021;25(2):117–118.