Cargando…

PrP(C) Aptamer Conjugated–Gold Nanoparticles for Targeted Delivery of Doxorubicin to Colorectal Cancer Cells

Anticancer drugs, such as fluorouracil (5-FU), oxaliplatin, and doxorubicin (Dox) are commonly used to treat colorectal cancer (CRC); however, owing to their low response rate and adverse effects, the development of efficient drug delivery systems (DDSs) is required. The cellular prion protein PrP(C...

Descripción completa

Detalles Bibliográficos
Autores principales:	Go, Gyeongyun, Lee, Chang-Seuk, Yoon, Yeo Min, Lim, Ji Ho, Kim, Tae Hyun, Lee, Sang Hun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922473/ https://www.ncbi.nlm.nih.gov/pubmed/33671292 http://dx.doi.org/10.3390/ijms22041976

Ejemplares similares

Unraveling Prion Protein Interactions with Aptamers and Other PrP-Binding Nucleic Acids
por: Macedo, Bruno, et al.
Publicado: (2017)

Aptamer–drug conjugate: targeted delivery of doxorubicin in a HER3 aptamer-functionalized liposomal delivery system reduces cardiotoxicity
por: Dou, Xiao-qian, et al.
Publicado: (2018)

Development and structural determination of an anti-PrP(C) aptamer that blocks pathological conformational conversion of prion protein
por: Mashima, Tsukasa, et al.
Publicado: (2020)

Interaction of Peptide Aptamers with Prion Protein Central Domain Promotes α-Cleavage of PrP(C)
por: Corda, Erica, et al.
Publicado: (2018)

Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
por: Sakudo, Akikazu, et al.
Publicado: (2015)

Targeted delivery of doxorubicin and therapeutic FOXM1 aptamer to tumor cells using gold nanoparticles modified with AS1411 and ATP aptamers
por: Abdollahzade, Aref, et al.
Publicado: (2023)

Early Delivery of Misfolded PrP from ER to Lysosomes by Autophagy
por: Cortes, Constanza J., et al.
Publicado: (2013)

TUDCA-treated chronic kidney disease-derived hMSCs improve therapeutic efficacy in ischemic disease via PrP(C)
por: Yoon, Yeo Min, et al.
Publicado: (2019)

The Structure of PrP(Sc) Prions
por: Wille, Holger, et al.
Publicado: (2018)

Knockdown of CK2α reduces P-cresol-induced fibrosis in human renal proximal tubule epithelial cells via the downregulation of profilin-1
por: Yoon, Yeo Min, et al.
Publicado: (2020)

Doxorubicin-Conjugated Innovative 16-mer DNA Aptamer-Based Annexin A1 Targeted Anti-Cancer Drug Delivery
por: Bavi, Rohit, et al.
Publicado: (2020)

PrP Expression, PrP(Sc) Accumulation and Innervation of Splenic Compartments in Sheep Experimentally Infected with Scrapie
por: Sørby, Randi, et al.
Publicado: (2009)

Anti-Prion Drug mPPIg5 Inhibits PrP(C) Conversion to PrP(Sc)
por: McCarthy, James M., et al.
Publicado: (2013)

Infectivity-associated PrP(Sc) and disease duration-associated PrP(Sc) of mouse BSE prions
por: Miyazawa, Kohtaro, et al.
Publicado: (2015)

The native state of prion protein (PrP) directly inhibits formation of PrP-amyloid fibrils in vitro
por: Honda, Ryo P., et al.
Publicado: (2017)

Prion Protein of Extracellular Vesicle Regulates the Progression of Colorectal Cancer
por: Yun, Chul-Won, et al.
Publicado: (2021)

Predicting the consequences of selecting on PrP genotypes on PrP frequencies, performance and inbreeding in commercial meat sheep populations
por: Man, Wing-Young N, et al.
Publicado: (2007)

PK-sensitive PrP(Sc) Is Infectious and Shares Basic Structural Features with PK-resistant PrP(Sc)
por: Sajnani, Gustavo, et al.
Publicado: (2012)

Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis
por: Yoon, Yeo Min, et al.
Publicado: (2021)

Melatonin Protects Chronic Kidney Disease Mesenchymal Stem/Stromal Cells against Accumulation of Methylglyoxal via Modulation of Hexokinase-2 Expression
por: Go, Gyeongyun, et al.
Publicado: (2022)

Aptamer-Aptamer Chimera for Targeted Delivery and ATP-Responsive Release of Doxorubicin into Cancer Cells
por: Esawi, Ezaldeen, et al.
Publicado: (2021)

Melatonin Suppresses Renal Cortical Fibrosis by Inhibiting Cytoskeleton Reorganization and Mitochondrial Dysfunction through Regulation of miR-4516
por: Yoon, Yeo Min, et al.
Publicado: (2020)

Small Protease Sensitive Oligomers of PrP(Sc) in Distinct Human Prions Determine Conversion Rate of PrP(C)
por: Kim, Chae, et al.
Publicado: (2012)

Glimepiride Reduces the Expression of PrP(C), Prevents PrP(Sc) Formation and Protects against Prion Mediated Neurotoxicity
por: Bate, Clive, et al.
Publicado: (2009)

A Camelid Anti-PrP Antibody Abrogates PrP(Sc) Replication in Prion-Permissive Neuroblastoma Cell Lines
por: Jones, Daryl Rhys, et al.
Publicado: (2010)

Identifying critical sites of PrP(c)-PrP(Sc) interaction in prion-infected cells by dominant-negative inhibition
por: Taguchi, Yuzuru, et al.
Publicado: (2013)

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions
por: Barron, Rona M., et al.
Publicado: (2016)

Recombinant PrP(Sc) shares structural features with brain-derived PrP(Sc): Insights from limited proteolysis
por: Sevillano, Alejandro M., et al.
Publicado: (2018)

Exploration of the Main Sites for the Transformation of Normal Prion Protein (PrP(C)) into Pathogenic Prion Protein (PrP(sc))
por: Liu, Xi-Lin, et al.
Publicado: (2017)

Melatonin Protects Human Renal Proximal Tubule Epithelial Cells Against High Glucose-Mediated Fibrosis via the Cellular Prion Protein-TGF-β-Smad Signaling Axis
por: Han, Yong-Seok, et al.
Publicado: (2020)

Aptamer-conjugated gold nanoparticles and their diagnostic and therapeutic roles in cancer
por: Deng, Guozhen, et al.
Publicado: (2023)

Gold Nanorods Conjugated with Doxorubicin and cRGD for Combined Anticancer Drug Delivery and PET Imaging
por: Xiao, Yuling, et al.
Publicado: (2012)

Correction: Yun et al. Prion Protein of Extracellular Vesicle Regulates the Progression of Colorectal Cancer. Cancers 2021, 13, 2144
por: Yun, Chul-Won, et al.
Publicado: (2021)

Na(+)/K(+)-ATPase Is Present in Scrapie-Associated Fibrils, Modulates PrP Misfolding In Vitro and Links PrP Function and Dysfunction
por: Graham, James F., et al.
Publicado: (2011)

Nanopore Analysis of Wild-Type and Mutant Prion Protein (PrP(C)): Single Molecule Discrimination and PrP(C) Kinetics
por: Jetha, Nahid N., et al.
Publicado: (2013)

Heterogeneity of Abnormal Prion Protein (PrP(Sc)) in Murine Scrapie Prions Determined by PrP(Sc)-Specific Monoclonal Antibodies
por: USHIKI-KAKU, Yuko, et al.
Publicado: (2013)

The ZIP5 Ectodomain Co-Localizes with PrP and May Acquire a PrP-Like Fold That Assembles into a Dimer
por: Pocanschi, Cosmin L., et al.
Publicado: (2013)

PrP(ST), a Soluble, Protease Resistant and Truncated PrP Form Features in the Pathogenesis of a Genetic Prion Disease
por: Friedman-Levi, Yael, et al.
Publicado: (2013)

Low fraction of the 222K PrP variant in the protease-resistant moiety of PrP(res) in heterozygous scrapie positive goats
por: Mazza, Maria, et al.
Publicado: (2017)

Enhancement of binding avidity by bivalent binding enables PrP(Sc)-specific detection by anti-PrP monoclonal antibody 132
por: Suzuki, Akio, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_3asit5kmaadhfj3jin55s9ql7m