Cargando…

The Role of the Pathologist in the Next-Generation Era of Tumor Molecular Characterization

Current pathology practice is being shaped by the increasing complexity of modern medicine, in particular of precision oncology, and major technological advances. In the “next-generation technologies era”, the pathologist has become the person responsible for the integration and interpretation of mo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Angerilli, Valentina, Galuppini, Francesca, Pagni, Fabio, Fusco, Nicola, Malapelle, Umberto, Fassan, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922586/ https://www.ncbi.nlm.nih.gov/pubmed/33670699 http://dx.doi.org/10.3390/diagnostics11020339

Ejemplares similares

FFPE-Based NGS Approaches into Clinical Practice: The Limits of Glory from a Pathologist Viewpoint
por: Cappello, Filippo, et al.
Publicado: (2022)

The ideal reporting of RAS testing in colorectal adenocarcinoma: a pathologists’ perspective
por: Malapelle, Umberto, et al.
Publicado: (2023)

Next-Generation Sequencing in Tumor Diagnosis and Treatment
por: de Biase, Dario, et al.
Publicado: (2020)

Current molecular biomarkers evaluation in gastric/gastroesophageal junction adenocarcinoma: pathologist does matter
por: Businello, Gianluca, et al.
Publicado: (2022)

Special Issue: Next-Generation Sequencing in Tumor Diagnosis and Treatment II
por: Malapelle, Umberto, et al.
Publicado: (2022)

Editorial: Molecular Characterization of Thyroid Lesions in the Era of “Next-Generation” Techniques
por: Bellevicine, Claudio, et al.
Publicado: (2022)

FGFR2 testing in cholangiocarcinoma: translating molecular studies into clinical practice
por: Angerilli, Valentina, et al.
Publicado: (2023)

Molecular subtyping of gastroesophageal dysplasia heterogeneity according to TCGA/ACRG classes
por: Angerilli, Valentina, et al.
Publicado: (2022)

Microsatellite Instable Colorectal Adenocarcinoma Diagnostics: The Advent of Liquid Biopsy Approaches
por: Ceccon, Carlotta, et al.
Publicado: (2022)

The GIPAD handbook of the gastrointestinal pathologist (in the Covid-19 era)
por: Parente, Paola, et al.
Publicado: (2020)

miRNAs Involved in Esophageal Carcinogenesis and miRNA-Related Therapeutic Perspectives in Esophageal Carcinoma
por: Zarrilli, Giovanni, et al.
Publicado: (2021)

Molecular Landscapes of Gastric Pre-Neoplastic and Pre-Invasive Lesions
por: Businello, Gianluca, et al.
Publicado: (2021)

MicroRNAs as Predictive Biomarkers of Resistance to Targeted Therapies in Gastrointestinal Tumors
por: Angerilli, Valentina, et al.
Publicado: (2021)

Atlas of PD-L1 for Pathologists: Indications, Scores, Diagnostic Platforms and Reporting Systems
por: Marletta, Stefano, et al.
Publicado: (2022)

Molecular and Morphological Profiling of Lung Cancer: A Foundation for “Next-Generation” Pathologists and Oncologists
por: Kashima, Jumpei, et al.
Publicado: (2019)

Tumor heterogeneity: next-generation sequencing enhances the view from the pathologist’s microscope
por: Aparicio, Samuel, et al.
Publicado: (2014)

Editorial: Diagnosis and Treatment of Breast Cancer in 2022: The Rise of Novel Molecular Biomarkers
por: Fusco, Nicola, et al.
Publicado: (2023)

Molecular Characterization of Thyroid Follicular Lesions in the Era of “Next-Generation” Techniques
por: Rossi, Esther Diana, et al.
Publicado: (2022)

PIK3CA Mutations as a Molecular Target for Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer
por: Fusco, Nicola, et al.
Publicado: (2021)

Next-Generation Sequencing of Lung Cancer EGFR Exons 18-21 Allows Effective Molecular Diagnosis of Small Routine Samples (Cytology and Biopsy)
por: de Biase, Dario, et al.
Publicado: (2013)

Current role of non-coding RNAs in the clinical setting
por: Vicentini, Caterina, et al.
Publicado: (2019)

The Role of the Toxicologic Pathologist in the Post-Genomic Era(#)
por: Maronpot, Robert R.
Publicado: (2013)

Molecular Modelling Hurdle in the Next-Generation Sequencing Era
por: Fernandez, Guerau, et al.
Publicado: (2022)

Tissue management in precision medicine: What the pathologist needs to know in the molecular era
por: Souza da Silva, Ricella, et al.
Publicado: (2022)

Targeting Immune-Related Biological Processes in Solid Tumors: We do Need Biomarkers
por: Pagni, Fabio, et al.
Publicado: (2019)

Next generation sequencing in cytology
por: Pisapia, Pasquale, et al.
Publicado: (2021)

Pathologist’s approach to paediatric and neonatal eosinophilic gastrointestinal disorders
por: Campora, Michela, et al.
Publicado: (2022)

Editorial: Concomitant pathogenic mutations in oncogene-driven subgroups: when next generation biology meets targeted therapy in NSCLC
por: Malapelle, Umberto, et al.
Publicado: (2023)

Next Generation Sequencing and Genetic Alterations in Squamous Cell Lung Carcinoma: Where Are We Today?
por: Friedlaender, Alex, et al.
Publicado: (2019)

The molecular landscape of breast mucoepidermoid carcinoma
por: Venetis, Konstantinos, et al.
Publicado: (2023)

Tumor mutation burden: from comprehensive mutational screening to the clinic
por: Galuppini, Francesca, et al.
Publicado: (2019)

HER2 aberrations and heterogeneity in cancers of the digestive system: Implications for pathologists and gastroenterologists
por: Fusco, Nicola, et al.
Publicado: (2016)

Targeted therapy and non-small cell lung cancer: a new era!
por: Malapelle, Umberto, et al.
Publicado: (2019)

The Reproducibility of the Immunohistochemical PD-L1 Testing in Non-Small-Cell Lung Cancer: A Multicentric Italian Experience
por: Vigliar, Elena, et al.
Publicado: (2019)

Molecular heterogeneity assessment by next-generation sequencing and response to gefitinib of EGFR mutant advanced lung adenocarcinoma
por: Bria, Emilio, et al.
Publicado: (2015)

Preoperative endoscopy and pathology report of the specimen to be recommended in sleeve gastrectomy?
por: Alessandris, Remo, et al.
Publicado: (2023)

Molecular Typing of Lung Adenocarcinoma on Cytological Samples Using a Multigene Next Generation Sequencing Panel
por: Scarpa, Aldo, et al.
Publicado: (2013)

The path to next generation biofuels: successes and challenges in the era of synthetic biology
por: Dellomonaco, Clementina, et al.
Publicado: (2010)

Challenges in Molecular Diagnostics of Channelopathies in the Next-Generation Sequencing Era: Less Is More?
por: Novelli, Valeria, et al.
Publicado: (2016)

The next frontier of early lung cancer and minimal residual disease detection: is multiomics the solution?
por: Rolfo, Christian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nqbr10veug355bojutp26ktqai