Cargando…

Mitochondriopathies as a Clue to Systemic Disorders—Analytical Tools and Mitigating Measures in Context of Predictive, Preventive, and Personalized (3P) Medicine

The mitochondrial respiratory chain is the main site of reactive oxygen species (ROS) production in the cell. Although mitochondria possess a powerful antioxidant system, an excess of ROS cannot be completely neutralized and cumulative oxidative damage may lead to decreasing mitochondrial efficiency...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liskova, Alena, Samec, Marek, Koklesova, Lenka, Kudela, Erik, Kubatka, Peter, Golubnitschaja, Olga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922866/ https://www.ncbi.nlm.nih.gov/pubmed/33670490 http://dx.doi.org/10.3390/ijms22042007

Ejemplares similares

Protective Effects of Flavonoids Against Mitochondriopathies and Associated Pathologies: Focus on the Predictive Approach and Personalized Prevention
por: Koklesova, Lenka, et al.
Publicado: (2021)

Mitochondrial health quality control: measurements and interpretation in the framework of predictive, preventive, and personalized medicine
por: Koklesova, Lenka, et al.
Publicado: (2022)

Liquid Biopsy is Instrumental for 3PM Dimensional Solutions in Cancer Management
por: Liskova, Alena, et al.
Publicado: (2020)

Therapy-resistant breast cancer in focus: Clinically relevant mitigation by flavonoids targeting cancer stem cells
por: Mazurakova, Alena, et al.
Publicado: (2023)

Targeting phytoprotection in the COVID-19-induced lung damage and associated systemic effects—the evidence-based 3PM proposition to mitigate individual risks
por: Liskova, Alena, et al.
Publicado: (2021)

Cell-free nucleic acid patterns in disease prediction and monitoring—hype or hope?
por: Crigna, Adriana Torres, et al.
Publicado: (2020)

Mitochondrial impairments in aetiopathology of multifactorial diseases: common origin but individual outcomes in context of 3P medicine
por: Koklesova, Lenka, et al.
Publicado: (2021)

Homocysteine metabolism as the target for predictive medical approach, disease prevention, prognosis, and treatments tailored to the person
por: Koklesova, Lenka, et al.
Publicado: (2021)

miRNA Expression Profiles in Luminal A Breast Cancer—Implications in Biology, Prognosis, and Prediction of Response to Hormonal Treatment
por: Kudela, Erik, et al.
Publicado: (2020)

Anti-prostate cancer protection and therapy in the framework of predictive, preventive and personalised medicine — comprehensive effects of phytochemicals in primary, secondary and tertiary care
por: Mazurakova, Alena, et al.
Publicado: (2022)

Rho GTPases in Gynecologic Cancers: In-Depth Analysis toward the Paradigm Change from Reactive to Predictive, Preventive, and Personalized Medical Approach Benefiting the Patient and Healthcare
por: Zubor, Pavol, et al.
Publicado: (2020)

Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back
por: Koklesova, Lenka, et al.
Publicado: (2020)

Carotenoids in Cancer Metastasis—Status Quo and Outlook
por: Koklesova, Lenka, et al.
Publicado: (2020)

Antithrombotic and antiplatelet effects of plant-derived compounds: a great utility potential for primary, secondary, and tertiary care in the framework of 3P medicine
por: Kubatka, Peter, et al.
Publicado: (2022)

Phytochemical-based nanodrugs going beyond the state-of-the-art in cancer management—Targeting cancer stem cells in the framework of predictive, preventive, personalized medicine
por: Koklesova, Lenka, et al.
Publicado: (2023)

Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles
por: Liskova, Alena, et al.
Publicado: (2021)

Genoprotective activities of plant natural substances in cancer and chemopreventive strategies in the context of 3P medicine
por: Koklesova, Lenka, et al.
Publicado: (2020)

Flavonoids in Cancer Metastasis
por: Liskova, Alena, et al.
Publicado: (2020)

Cold Atmospheric Pressure Plasma (CAP) as a New Tool for the Management of Vulva Cancer and Vulvar Premalignant Lesions in Gynaecological Oncology
por: Zubor, Pavol, et al.
Publicado: (2020)

Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care
por: Mazurakova, Alena, et al.
Publicado: (2022)

Counteracting Chemoresistance with Metformin in Breast Cancers: Targeting Cancer Stem Cells
por: Samuel, Samson Mathews, et al.
Publicado: (2020)

Metabolic Anti-Cancer Effects of Melatonin: Clinically Relevant Prospects
por: Samec, Marek, et al.
Publicado: (2021)

Breast Cancer in Young Women: Status Quo and Advanced Disease Management by a Predictive, Preventive, and Personalized Approach
por: Kudela, Erik, et al.
Publicado: (2019)

Tamoxifen and oxidative stress: an overlooked connection
por: Ahmed, Nermin S., et al.
Publicado: (2021)

Diabetic retinopathy as the leading cause of blindness and early predictor of cascading complications—risks and mitigation
por: Kropp, Martina, et al.
Publicado: (2023)

Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism
por: Samec, Marek, et al.
Publicado: (2020)

Genetic Heterogeneity, Tumor Microenvironment and Immunotherapy in Triple-Negative Breast Cancer
por: Kudelova, Eva, et al.
Publicado: (2022)

Flavonoids against non-physiologic inflammation attributed to cancer initiation, development, and progression—3PM pathways
por: Kubatka, Peter, et al.
Publicado: (2021)

Fluctuations of Histone Chemical Modifications in Breast, Prostate, and Colorectal Cancer: An Implication of Phytochemicals as Defenders of Chromatin Equilibrium
por: Samec, Marek, et al.
Publicado: (2019)

Paclitaxel’s Mechanistic and Clinical Effects on Breast Cancer
por: Abu Samaan, Tala M., et al.
Publicado: (2019)

Anticancer Potential of Lichens’ Secondary Metabolites
por: Solárová, Zuzana, et al.
Publicado: (2020)

Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies
por: Swerdlow, Russell H.
Publicado: (2009)

Targeting Glucose Metabolism to Overcome Resistance to Anticancer Chemotherapy in Breast Cancer
por: Varghese, Elizabeth, et al.
Publicado: (2020)

Pre-pregnancy check-up of maternal vascular status and associated phenotype is crucial for the health of mother and offspring
por: Evsevieva, Maria, et al.
Publicado: (2022)

Why the Gold Standard Approach by Mammography Demands Extension by Multiomics? Application of Liquid Biopsy miRNA Profiles to Breast Cancer Disease Management
por: Zubor, Pavol, et al.
Publicado: (2019)

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
por: Kubatka, Peter, et al.
Publicado: (2020)

Chromium and cobalt intoxication mimicking mitochondriopathy
por: Rattay, Tim W., et al.
Publicado: (2021)

Systemic Effects Reflected in Specific Biomarker Patterns Are Instrumental for the Paradigm Change in Prostate Cancer Management: A Strategic Paper
por: Golubnitschaja, Olga, et al.
Publicado: (2022)

Endothelin-1 axes in the framework of predictive, preventive and personalised (3P) medicine
por: Torres Crigna, Adriana, et al.
Publicado: (2021)

Caution, “normal” BMI: health risks associated with potentially masked individual underweight—EPMA Position Paper 2021
por: Golubnitschaja, Olga, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_clibi8k0tnaojddlpciemg9sst