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Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping

Three-directional cine multi-slice left ventricular myocardial velocity mapping (3Dir MVM) is a cardiac magnetic resonance (CMR) technique that allows the assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the myocardium is crucial for accurate anal...

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Autores principales: Wu, Yinzhe, Hatipoglu, Suzan, Alonso-Álvarez, Diego, Gatehouse, Peter, Li, Binghuan, Gao, Yikai, Firmin, David, Keegan, Jennifer, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922945/
https://www.ncbi.nlm.nih.gov/pubmed/33669747
http://dx.doi.org/10.3390/diagnostics11020346
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author Wu, Yinzhe
Hatipoglu, Suzan
Alonso-Álvarez, Diego
Gatehouse, Peter
Li, Binghuan
Gao, Yikai
Firmin, David
Keegan, Jennifer
Yang, Guang
author_facet Wu, Yinzhe
Hatipoglu, Suzan
Alonso-Álvarez, Diego
Gatehouse, Peter
Li, Binghuan
Gao, Yikai
Firmin, David
Keegan, Jennifer
Yang, Guang
author_sort Wu, Yinzhe
collection PubMed
description Three-directional cine multi-slice left ventricular myocardial velocity mapping (3Dir MVM) is a cardiac magnetic resonance (CMR) technique that allows the assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the myocardium is crucial for accurate analysis of peak systolic and diastolic myocardial velocities. In addition to the conventionally available magnitude CMR data, 3Dir MVM also provides three orthogonal phase velocity mapping datasets, which are used to generate velocity maps. These velocity maps may also be used to facilitate and improve the myocardial delineation. Based on the success of deep learning in medical image processing, we propose a novel fast and automated framework that improves the standard U-Net-based methods on these CMR multi-channel data (magnitude and phase velocity mapping) by cross-channel fusion with an attention module and the shape information-based post-processing to achieve accurate delineation of both epicardial and endocardial contours. To evaluate the results, we employ the widely used Dice Scores and the quantification of myocardial longitudinal peak velocities. Our proposed network trained with multi-channel data shows superior performance compared to standard U-Net-based networks trained on single-channel data. The obtained results are promising and provide compelling evidence for the design and application of our multi-channel image analysis of the 3Dir MVM CMR data.
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spelling pubmed-79229452021-03-03 Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping Wu, Yinzhe Hatipoglu, Suzan Alonso-Álvarez, Diego Gatehouse, Peter Li, Binghuan Gao, Yikai Firmin, David Keegan, Jennifer Yang, Guang Diagnostics (Basel) Article Three-directional cine multi-slice left ventricular myocardial velocity mapping (3Dir MVM) is a cardiac magnetic resonance (CMR) technique that allows the assessment of cardiac motion in three orthogonal directions. Accurate and reproducible delineation of the myocardium is crucial for accurate analysis of peak systolic and diastolic myocardial velocities. In addition to the conventionally available magnitude CMR data, 3Dir MVM also provides three orthogonal phase velocity mapping datasets, which are used to generate velocity maps. These velocity maps may also be used to facilitate and improve the myocardial delineation. Based on the success of deep learning in medical image processing, we propose a novel fast and automated framework that improves the standard U-Net-based methods on these CMR multi-channel data (magnitude and phase velocity mapping) by cross-channel fusion with an attention module and the shape information-based post-processing to achieve accurate delineation of both epicardial and endocardial contours. To evaluate the results, we employ the widely used Dice Scores and the quantification of myocardial longitudinal peak velocities. Our proposed network trained with multi-channel data shows superior performance compared to standard U-Net-based networks trained on single-channel data. The obtained results are promising and provide compelling evidence for the design and application of our multi-channel image analysis of the 3Dir MVM CMR data. MDPI 2021-02-19 /pmc/articles/PMC7922945/ /pubmed/33669747 http://dx.doi.org/10.3390/diagnostics11020346 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wu, Yinzhe
Hatipoglu, Suzan
Alonso-Álvarez, Diego
Gatehouse, Peter
Li, Binghuan
Gao, Yikai
Firmin, David
Keegan, Jennifer
Yang, Guang
Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping
title Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping
title_full Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping
title_fullStr Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping
title_full_unstemmed Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping
title_short Fast and Automated Segmentation for the Three-Directional Multi-Slice Cine Myocardial Velocity Mapping
title_sort fast and automated segmentation for the three-directional multi-slice cine myocardial velocity mapping
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7922945/
https://www.ncbi.nlm.nih.gov/pubmed/33669747
http://dx.doi.org/10.3390/diagnostics11020346
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