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Extensive Histopathological Characterization of Inflamed Bowel in the Dextran Sulfate Sodium Mouse Model with Emphasis on Clinically Relevant Biomarkers and Targets for Drug Development

This study aims to develop a reliable and reproducible inflammatory bowel disease (IBD) murine model based on a careful spatial–temporal histological characterization. Secondary aims included extensive preclinical studies focused on the in situ expression of clinically relevant biomarkers and target...

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Detalles Bibliográficos
Autores principales: Bonfiglio, Rita, Galli, Filippo, Varani, Michela, Scimeca, Manuel, Borri, Filippo, Fazi, Sara, Cicconi, Rosella, Mattei, Maurizio, Campagna, Giuseppe, Schönberger, Tanja, Raymond, Ernest, Wunder, Andreas, Signore, Alberto, Bonanno, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923003/
https://www.ncbi.nlm.nih.gov/pubmed/33670766
http://dx.doi.org/10.3390/ijms22042028