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Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy

Pneumocystis jirovecii pneumonia (PJP) is one type of life-threatening pneumonia in immunocompromised patients. PJP development should be considered in not only immunocompromised individuals, but also patients undergoing intensive chemotherapies and immunotherapies, organ transplantation, or cortico...

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Detalles Bibliográficos
Autores principales: Takeuchi, Kazuto, Yakushijin, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923143/
https://www.ncbi.nlm.nih.gov/pubmed/33669742
http://dx.doi.org/10.3390/pathogens10020237
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author Takeuchi, Kazuto
Yakushijin, Yoshihiro
author_facet Takeuchi, Kazuto
Yakushijin, Yoshihiro
author_sort Takeuchi, Kazuto
collection PubMed
description Pneumocystis jirovecii pneumonia (PJP) is one type of life-threatening pneumonia in immunocompromised patients. PJP development should be considered in not only immunocompromised individuals, but also patients undergoing intensive chemotherapies and immunotherapies, organ transplantation, or corticosteroid treatment. Past studies have described the clinical manifestation of PJP in patients during chemotherapy and reported that PJP affects cancer treatment outcomes. Therefore, PJP could be a potential problem for the management of cancer patients during chemotherapy, and PJP prophylaxis would be important during cancer treatment. This review discusses PJ colonization in outpatients during cancer chemotherapy, as well as in healthy individuals, and provides an update on PJP prophylaxis for cancer patients during chemotherapy.
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spelling pubmed-79231432021-03-03 Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy Takeuchi, Kazuto Yakushijin, Yoshihiro Pathogens Review Pneumocystis jirovecii pneumonia (PJP) is one type of life-threatening pneumonia in immunocompromised patients. PJP development should be considered in not only immunocompromised individuals, but also patients undergoing intensive chemotherapies and immunotherapies, organ transplantation, or corticosteroid treatment. Past studies have described the clinical manifestation of PJP in patients during chemotherapy and reported that PJP affects cancer treatment outcomes. Therefore, PJP could be a potential problem for the management of cancer patients during chemotherapy, and PJP prophylaxis would be important during cancer treatment. This review discusses PJ colonization in outpatients during cancer chemotherapy, as well as in healthy individuals, and provides an update on PJP prophylaxis for cancer patients during chemotherapy. MDPI 2021-02-19 /pmc/articles/PMC7923143/ /pubmed/33669742 http://dx.doi.org/10.3390/pathogens10020237 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Takeuchi, Kazuto
Yakushijin, Yoshihiro
Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
title Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
title_full Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
title_fullStr Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
title_full_unstemmed Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
title_short Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
title_sort pneumocystis jirovecii pneumonia prophylaxis for cancer patients during chemotherapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923143/
https://www.ncbi.nlm.nih.gov/pubmed/33669742
http://dx.doi.org/10.3390/pathogens10020237
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