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Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy
Pneumocystis jirovecii pneumonia (PJP) is one type of life-threatening pneumonia in immunocompromised patients. PJP development should be considered in not only immunocompromised individuals, but also patients undergoing intensive chemotherapies and immunotherapies, organ transplantation, or cortico...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923143/ https://www.ncbi.nlm.nih.gov/pubmed/33669742 http://dx.doi.org/10.3390/pathogens10020237 |
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author | Takeuchi, Kazuto Yakushijin, Yoshihiro |
author_facet | Takeuchi, Kazuto Yakushijin, Yoshihiro |
author_sort | Takeuchi, Kazuto |
collection | PubMed |
description | Pneumocystis jirovecii pneumonia (PJP) is one type of life-threatening pneumonia in immunocompromised patients. PJP development should be considered in not only immunocompromised individuals, but also patients undergoing intensive chemotherapies and immunotherapies, organ transplantation, or corticosteroid treatment. Past studies have described the clinical manifestation of PJP in patients during chemotherapy and reported that PJP affects cancer treatment outcomes. Therefore, PJP could be a potential problem for the management of cancer patients during chemotherapy, and PJP prophylaxis would be important during cancer treatment. This review discusses PJ colonization in outpatients during cancer chemotherapy, as well as in healthy individuals, and provides an update on PJP prophylaxis for cancer patients during chemotherapy. |
format | Online Article Text |
id | pubmed-7923143 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-79231432021-03-03 Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy Takeuchi, Kazuto Yakushijin, Yoshihiro Pathogens Review Pneumocystis jirovecii pneumonia (PJP) is one type of life-threatening pneumonia in immunocompromised patients. PJP development should be considered in not only immunocompromised individuals, but also patients undergoing intensive chemotherapies and immunotherapies, organ transplantation, or corticosteroid treatment. Past studies have described the clinical manifestation of PJP in patients during chemotherapy and reported that PJP affects cancer treatment outcomes. Therefore, PJP could be a potential problem for the management of cancer patients during chemotherapy, and PJP prophylaxis would be important during cancer treatment. This review discusses PJ colonization in outpatients during cancer chemotherapy, as well as in healthy individuals, and provides an update on PJP prophylaxis for cancer patients during chemotherapy. MDPI 2021-02-19 /pmc/articles/PMC7923143/ /pubmed/33669742 http://dx.doi.org/10.3390/pathogens10020237 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Takeuchi, Kazuto Yakushijin, Yoshihiro Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy |
title | Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy |
title_full | Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy |
title_fullStr | Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy |
title_full_unstemmed | Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy |
title_short | Pneumocystis jirovecii Pneumonia Prophylaxis for Cancer Patients during Chemotherapy |
title_sort | pneumocystis jirovecii pneumonia prophylaxis for cancer patients during chemotherapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923143/ https://www.ncbi.nlm.nih.gov/pubmed/33669742 http://dx.doi.org/10.3390/pathogens10020237 |
work_keys_str_mv | AT takeuchikazuto pneumocystisjiroveciipneumoniaprophylaxisforcancerpatientsduringchemotherapy AT yakushijinyoshihiro pneumocystisjiroveciipneumoniaprophylaxisforcancerpatientsduringchemotherapy |