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Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats

Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by su...

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Autores principales: Rahman, Shaikh Shahinur, Salauddin, Hussain Mohammad, Rahman, Mahfuzur, Muhsin, Mir Mohammad, Rouf, Shakh MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923245/
https://www.ncbi.nlm.nih.gov/pubmed/33718629
http://dx.doi.org/10.1016/j.bbrep.2021.100917
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author Rahman, Shaikh Shahinur
Salauddin, Hussain Mohammad
Rahman, Mahfuzur
Muhsin, Mir Mohammad
Rouf, Shakh MA
author_facet Rahman, Shaikh Shahinur
Salauddin, Hussain Mohammad
Rahman, Mahfuzur
Muhsin, Mir Mohammad
Rouf, Shakh MA
author_sort Rahman, Shaikh Shahinur
collection PubMed
description Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by supplementary feeding powder of GESP, EFYT, and their mixture in addition to the regular diet for the six consecutive weeks. Next three weeks, the powder was withdrawn, and fasting blood glucose (FBG) levels were recorded from the beginning. The results clearly showed that these foodstuffs significantly (P < 0.001) reduced FBG levels of alloxan-induced diabetic rats. The mixture of GESP & EFYT showed the maximum antidiabetic effects followed by GESP and EFYT, respectively. GESP, as well as the mixture, returned the FBG levels of diabetic rats within the normal range by the end of the 6th week, even after withdrawing the powder, but not by the EFYT. These results suggested that the foodstuffs may restore the damaged pancreatic β-cell functions by the end of the 6th week. Nutrient contents like fiber, zinc, as well as antidiabetogenic phytochemicals present in these foodstuffs, could perform these functions.
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spelling pubmed-79232452021-03-12 Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats Rahman, Shaikh Shahinur Salauddin, Hussain Mohammad Rahman, Mahfuzur Muhsin, Mir Mohammad Rouf, Shakh MA Biochem Biophys Rep Research Article Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by supplementary feeding powder of GESP, EFYT, and their mixture in addition to the regular diet for the six consecutive weeks. Next three weeks, the powder was withdrawn, and fasting blood glucose (FBG) levels were recorded from the beginning. The results clearly showed that these foodstuffs significantly (P < 0.001) reduced FBG levels of alloxan-induced diabetic rats. The mixture of GESP & EFYT showed the maximum antidiabetic effects followed by GESP and EFYT, respectively. GESP, as well as the mixture, returned the FBG levels of diabetic rats within the normal range by the end of the 6th week, even after withdrawing the powder, but not by the EFYT. These results suggested that the foodstuffs may restore the damaged pancreatic β-cell functions by the end of the 6th week. Nutrient contents like fiber, zinc, as well as antidiabetogenic phytochemicals present in these foodstuffs, could perform these functions. Elsevier 2021-01-20 /pmc/articles/PMC7923245/ /pubmed/33718629 http://dx.doi.org/10.1016/j.bbrep.2021.100917 Text en © 2021 The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Research Article
Rahman, Shaikh Shahinur
Salauddin, Hussain Mohammad
Rahman, Mahfuzur
Muhsin, Mir Mohammad
Rouf, Shakh MA
Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
title Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
title_full Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
title_fullStr Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
title_full_unstemmed Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
title_short Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
title_sort nutritional composition and antidiabetic effect of germinated endosperm (borassus flabellifer), tuber (amorphophallus paeoniifolius) and their combined impact on rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923245/
https://www.ncbi.nlm.nih.gov/pubmed/33718629
http://dx.doi.org/10.1016/j.bbrep.2021.100917
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