Cargando…
Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats
Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by su...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923245/ https://www.ncbi.nlm.nih.gov/pubmed/33718629 http://dx.doi.org/10.1016/j.bbrep.2021.100917 |
_version_ | 1783658869808955392 |
---|---|
author | Rahman, Shaikh Shahinur Salauddin, Hussain Mohammad Rahman, Mahfuzur Muhsin, Mir Mohammad Rouf, Shakh MA |
author_facet | Rahman, Shaikh Shahinur Salauddin, Hussain Mohammad Rahman, Mahfuzur Muhsin, Mir Mohammad Rouf, Shakh MA |
author_sort | Rahman, Shaikh Shahinur |
collection | PubMed |
description | Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by supplementary feeding powder of GESP, EFYT, and their mixture in addition to the regular diet for the six consecutive weeks. Next three weeks, the powder was withdrawn, and fasting blood glucose (FBG) levels were recorded from the beginning. The results clearly showed that these foodstuffs significantly (P < 0.001) reduced FBG levels of alloxan-induced diabetic rats. The mixture of GESP & EFYT showed the maximum antidiabetic effects followed by GESP and EFYT, respectively. GESP, as well as the mixture, returned the FBG levels of diabetic rats within the normal range by the end of the 6th week, even after withdrawing the powder, but not by the EFYT. These results suggested that the foodstuffs may restore the damaged pancreatic β-cell functions by the end of the 6th week. Nutrient contents like fiber, zinc, as well as antidiabetogenic phytochemicals present in these foodstuffs, could perform these functions. |
format | Online Article Text |
id | pubmed-7923245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-79232452021-03-12 Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats Rahman, Shaikh Shahinur Salauddin, Hussain Mohammad Rahman, Mahfuzur Muhsin, Mir Mohammad Rouf, Shakh MA Biochem Biophys Rep Research Article Diabetic patients usually avoid germinated endosperm of sugar palm (GESP) and elephant foot yam tuber (EFYT), fearing that these may further deteriorate existing hyperglycemia. In the present study, this suspicion was investigated by analyzing the nutrients and following the animal experiments by supplementary feeding powder of GESP, EFYT, and their mixture in addition to the regular diet for the six consecutive weeks. Next three weeks, the powder was withdrawn, and fasting blood glucose (FBG) levels were recorded from the beginning. The results clearly showed that these foodstuffs significantly (P < 0.001) reduced FBG levels of alloxan-induced diabetic rats. The mixture of GESP & EFYT showed the maximum antidiabetic effects followed by GESP and EFYT, respectively. GESP, as well as the mixture, returned the FBG levels of diabetic rats within the normal range by the end of the 6th week, even after withdrawing the powder, but not by the EFYT. These results suggested that the foodstuffs may restore the damaged pancreatic β-cell functions by the end of the 6th week. Nutrient contents like fiber, zinc, as well as antidiabetogenic phytochemicals present in these foodstuffs, could perform these functions. Elsevier 2021-01-20 /pmc/articles/PMC7923245/ /pubmed/33718629 http://dx.doi.org/10.1016/j.bbrep.2021.100917 Text en © 2021 The Authors. Published by Elsevier B.V. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Research Article Rahman, Shaikh Shahinur Salauddin, Hussain Mohammad Rahman, Mahfuzur Muhsin, Mir Mohammad Rouf, Shakh MA Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats |
title | Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats |
title_full | Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats |
title_fullStr | Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats |
title_full_unstemmed | Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats |
title_short | Nutritional composition and antidiabetic effect of germinated endosperm (Borassus flabellifer), tuber (Amorphophallus paeoniifolius) and their combined impact on rats |
title_sort | nutritional composition and antidiabetic effect of germinated endosperm (borassus flabellifer), tuber (amorphophallus paeoniifolius) and their combined impact on rats |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923245/ https://www.ncbi.nlm.nih.gov/pubmed/33718629 http://dx.doi.org/10.1016/j.bbrep.2021.100917 |
work_keys_str_mv | AT rahmanshaikhshahinur nutritionalcompositionandantidiabeticeffectofgerminatedendospermborassusflabellifertuberamorphophalluspaeoniifoliusandtheircombinedimpactonrats AT salauddinhussainmohammad nutritionalcompositionandantidiabeticeffectofgerminatedendospermborassusflabellifertuberamorphophalluspaeoniifoliusandtheircombinedimpactonrats AT rahmanmahfuzur nutritionalcompositionandantidiabeticeffectofgerminatedendospermborassusflabellifertuberamorphophalluspaeoniifoliusandtheircombinedimpactonrats AT muhsinmirmohammad nutritionalcompositionandantidiabeticeffectofgerminatedendospermborassusflabellifertuberamorphophalluspaeoniifoliusandtheircombinedimpactonrats AT roufshakhma nutritionalcompositionandantidiabeticeffectofgerminatedendospermborassusflabellifertuberamorphophalluspaeoniifoliusandtheircombinedimpactonrats |