Novel methylated DNA markers accurately discriminate Lynch syndrome associated colorectal neoplasia

AIM: Acquired molecular changes in Lynch syndrome (LS) colorectal tumors have been largely unstudied. We identified methylated DNA markers (MDMs) for discrimination of colorectal neoplasia in LS and determined if these MDMs were comparably discriminant in sporadic patients. PATIENTS & METHODS: F...

Descripción completa

Detalles Bibliográficos
Autores principales: Ballester, Veroushka, Taylor, William R, Slettedahl, Seth W, Mahoney, Douglas W, Yab, Tracy C, Sinicrope, Frank A, Boland, Clement R, Lidgard, Graham P, Cruz-Correa, Marcia R, Smyrk, Thomas C, Boardman, Lisa A, Ahlquist, David A, Kisiel, John B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923255/
https://www.ncbi.nlm.nih.gov/pubmed/33350853
http://dx.doi.org/10.2217/epi-2020-0132

Ejemplares similares

Ejemplares similares