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Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis

The presence of islet cells double positive for insulin and glucagon (Ins(+)/Glu(+)) has been described in the pancreas from both type 2 (T2D) and type 1 (T1D) diabetic subjects. We studied the role of pro-inflammatory cytokines on the occurrence, trajectory, and characteristics of Ins(+)/Glu(+) cel...

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Detalles Bibliográficos
Autores principales:	Tesi, Marta, Bugliani, Marco, Ferri, Gianmarco, Suleiman, Mara, De Luca, Carmela, Bosi, Emanuele, Masini, Matilde, De Tata, Vincenzo, Gysemans, Conny, Cardarelli, Francesco, Cnop, Miriam, Eizirik, Decio L., Marchetti, Piero, Marselli, Lorella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923272/ https://www.ncbi.nlm.nih.gov/pubmed/33669901 http://dx.doi.org/10.3390/biom11020320

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