Use of the JAK Inhibitor Ruxolitinib in the Treatment of Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome driven by overactive T cells and macrophages that abundantly secrete numerous pro-inflammatory cytokines, including interferon (IFN)-gamma, interleukin (IL)-1-beta, IL-2, IL-6, IL-10, IL-18, and tumor necrosis factor (TNF)...

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Detalles Bibliográficos
Autores principales: Keenan, Camille, Nichols, Kim E., Albeituni, Sabrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923355/
https://www.ncbi.nlm.nih.gov/pubmed/33664745
http://dx.doi.org/10.3389/fimmu.2021.614704

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923355/
https://www.ncbi.nlm.nih.gov/pubmed/33664745
http://dx.doi.org/10.3389/fimmu.2021.614704

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