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Metformin activated AMPK signaling contributes to the alleviation of LPS-induced inflammatory responses in bovine mammary epithelial cells

BACKGROUND: Lipopolysaccharides (LPS) derived from gram-negative bacterial are often regarded as primary inducer of bovine mammary inflammation. This study evaluated the biological response of metformin activated AMPK signaling on LPS-induced inflammatory responses and metabolic changes in primary b...

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Detalles Bibliográficos
Autores principales: Xu, Tianle, Wu, Xinyue, Lu, Xubin, Liang, Yusheng, Mao, Yongjiang, Loor, Juan J., Yang, Zhangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923493/
https://www.ncbi.nlm.nih.gov/pubmed/33648513
http://dx.doi.org/10.1186/s12917-021-02797-x