Pluripotent stem cell-derived epithelium misidentified as brain microvascular endothelium requires ETS factors to acquire vascular fate

Cells derived from pluripotent sources in vitro must resemble those found in vivo as closely as possible at both transcriptional and functional levels in order to be a useful tool for studying diseases and developing therapeutics. Recently, differentiation of human pluripotent stem cells (hPSCs) int...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Tyler M., Houghton, Sean, Magdeldin, Tarig, Durán, José Gabriel Barcia, Minotti, Andrew P., Snead, Amanda, Sproul, Andrew, Nguyen, Duc-Huy T., Xiang, Jenny, Fine, Howard A., Rosenwaks, Zev, Studer, Lorenz, Rafii, Shahin, Agalliu, Dritan, Redmond, David, Lis, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923590/
https://www.ncbi.nlm.nih.gov/pubmed/33542154
http://dx.doi.org/10.1073/pnas.2016950118

Ejemplares similares

Ejemplares similares