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Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells

The metabolism of Chinese hamster ovary (CHO) cell lines is typically characterized by high rates of aerobic glycolysis with increased lactate formation, known as the ”Warburg” effect. Although this metabolic state can switch to lactate consumption, the involved regulations of the central metabolism...

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Detalles Bibliográficos
Autores principales:	Möller, Johannes, Bhat, Krathika, Guhl, Lotta, Pörtner, Ralf, Jandt, Uwe, Zeng, An‐Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923601/ https://www.ncbi.nlm.nih.gov/pubmed/33716610 http://dx.doi.org/10.1002/elsc.202000037

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