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Transiently structured head domains control intermediate filament assembly

Low complexity (LC) head domains 92 and 108 residues in length are, respectively, required for assembly of neurofilament light (NFL) and desmin intermediate filaments (IFs). As studied in isolation, these IF head domains interconvert between states of conformational disorder and labile, β-strand–enr...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoming, Lin, Yi, Kato, Masato, Mori, Eiichiro, Liszczak, Glen, Sutherland, Lillian, Sysoev, Vasiliy O., Murray, Dylan T., Tycko, Robert, McKnight, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923618/
https://www.ncbi.nlm.nih.gov/pubmed/33593918
http://dx.doi.org/10.1073/pnas.2022121118