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Compressive mechanical stress enhances susceptibility to interleukin-1 by increasing interleukin-1 receptor expression in 3D-cultured ATDC5 cells
BACKGROUND: Mechanical overload applied on the articular cartilage may play an important role in the pathogenesis of osteoarthritis. However, the mechanism of chondrocyte mechanotransduction is not fully understood. The purpose of this study was to assess the effects of compressive mechanical stress...
Autores principales: | Takeda, Yuki, Niki, Yasuo, Fukuhara, Yusuke, Fukuda, Yoshitsugu, Udagawa, Kazuhiko, Shimoda, Masayuki, Kikuchi, Toshiyuki, Kobayashi, Shu, Harato, Kengo, Miyamoto, Takeshi, Matsumoto, Morio, Nakamura, Masaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923672/ https://www.ncbi.nlm.nih.gov/pubmed/33648469 http://dx.doi.org/10.1186/s12891-021-04095-x |
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