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Accurate SNV detection in single cells by transposon-based whole-genome amplification of complementary strands
Single-nucleotide variants (SNVs), pertinent to aging and disease, occur sporadically in the human genome, hence necessitating single-cell measurements. However, detection of single-cell SNVs suffers from false positives (FPs) due to intracellular single-stranded DNA damage and the process of whole-...
Autores principales: | Xing, Dong, Tan, Longzhi, Chang, Chi-Han, Li, Heng, Xie, X. Sunney |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923680/ https://www.ncbi.nlm.nih.gov/pubmed/33593904 http://dx.doi.org/10.1073/pnas.2013106118 |
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