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Mycobacterium W. - An unusual side effect

OBJECTIVE: To present an interesting case of unusual side effect of Mycobacterium W. in an adult COVID 19 positive male and discuss its assessment and management. METHODS: - DESIGN: Case Report. SETTING: Tertiary care hospital. PATIENT: One. RESULTS: 70 years male was admitted with complaints of fev...

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Autores principales: Chawla, Rakesh K., Chawla, Aditya K., Chaudhary, Gaurav, Chopra, Kamal, Chawla, Madhav K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tuberculosis Association of India. Published by Elsevier B.V. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923955/
https://www.ncbi.nlm.nih.gov/pubmed/35379411
http://dx.doi.org/10.1016/j.ijtb.2021.02.013
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author Chawla, Rakesh K.
Chawla, Aditya K.
Chaudhary, Gaurav
Chopra, Kamal
Chawla, Madhav K.
author_facet Chawla, Rakesh K.
Chawla, Aditya K.
Chaudhary, Gaurav
Chopra, Kamal
Chawla, Madhav K.
author_sort Chawla, Rakesh K.
collection PubMed
description OBJECTIVE: To present an interesting case of unusual side effect of Mycobacterium W. in an adult COVID 19 positive male and discuss its assessment and management. METHODS: - DESIGN: Case Report. SETTING: Tertiary care hospital. PATIENT: One. RESULTS: 70 years male was admitted with complaints of fever, persistent dry cough since 10–12 days and progressive breathlessness since 3–4 days. Patient was found COVID-19 RTPCR positive and is known case of Type-II Diabetes with CAD (Post PTCA). Patient was managed conservatively with Oxygen support, I/V antibiotics, I/V Steroids, oral Favipiravir and other supportive treatment. Patient was also given injection Mycobacterium W. in dose of 0.3 ml per day intradermally at 3 different sites (both deltoids) consecutively for three days. 7–8 days after administration, patient developed bright red pustules which later got converted into small punched out ulcerations on all nine local sites of administration, which were managed conservatively with oral analgesics and local steroids for 8–10 days which healed without any scar formation. CONCLUSION: Injection Mycobacterium W. is used in COVID 19 patients as an immunomodulator agent and has been proved to be safe in most of the cases but we encountered this unusual side effect of bright red pustules formation at all nine local sites of injection in our case most likely because of being administered subcutaneously instead of intradermally, making this an interesting case which is being reported to scientific fraternity.
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spelling pubmed-79239552021-03-03 Mycobacterium W. - An unusual side effect Chawla, Rakesh K. Chawla, Aditya K. Chaudhary, Gaurav Chopra, Kamal Chawla, Madhav K. Indian J Tuberc Case Report OBJECTIVE: To present an interesting case of unusual side effect of Mycobacterium W. in an adult COVID 19 positive male and discuss its assessment and management. METHODS: - DESIGN: Case Report. SETTING: Tertiary care hospital. PATIENT: One. RESULTS: 70 years male was admitted with complaints of fever, persistent dry cough since 10–12 days and progressive breathlessness since 3–4 days. Patient was found COVID-19 RTPCR positive and is known case of Type-II Diabetes with CAD (Post PTCA). Patient was managed conservatively with Oxygen support, I/V antibiotics, I/V Steroids, oral Favipiravir and other supportive treatment. Patient was also given injection Mycobacterium W. in dose of 0.3 ml per day intradermally at 3 different sites (both deltoids) consecutively for three days. 7–8 days after administration, patient developed bright red pustules which later got converted into small punched out ulcerations on all nine local sites of administration, which were managed conservatively with oral analgesics and local steroids for 8–10 days which healed without any scar formation. CONCLUSION: Injection Mycobacterium W. is used in COVID 19 patients as an immunomodulator agent and has been proved to be safe in most of the cases but we encountered this unusual side effect of bright red pustules formation at all nine local sites of injection in our case most likely because of being administered subcutaneously instead of intradermally, making this an interesting case which is being reported to scientific fraternity. Tuberculosis Association of India. Published by Elsevier B.V. 2022-04 2021-03-02 /pmc/articles/PMC7923955/ /pubmed/35379411 http://dx.doi.org/10.1016/j.ijtb.2021.02.013 Text en © 2021 Tuberculosis Association of India. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Chawla, Rakesh K.
Chawla, Aditya K.
Chaudhary, Gaurav
Chopra, Kamal
Chawla, Madhav K.
Mycobacterium W. - An unusual side effect
title Mycobacterium W. - An unusual side effect
title_full Mycobacterium W. - An unusual side effect
title_fullStr Mycobacterium W. - An unusual side effect
title_full_unstemmed Mycobacterium W. - An unusual side effect
title_short Mycobacterium W. - An unusual side effect
title_sort mycobacterium w. - an unusual side effect
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923955/
https://www.ncbi.nlm.nih.gov/pubmed/35379411
http://dx.doi.org/10.1016/j.ijtb.2021.02.013
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