Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Cancer Treatment trial

BACKGROUND: Molecular profiling (MP) represents an opportunity to match patients to a targeted therapy and when tumor tissue is unavailable, circulating tumor deoxyribonucleic acid (ctDNA) can be harnessed as a non-invasive analyte for this purpose. We evaluated the success of a targeted therapy sel...

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Detalles Bibliográficos
Autores principales: Riedl, Jakob M., Hasenleithner, Samantha O., Pregartner, Gudrun, Scheipner, Lukas, Posch, Florian, Groller, Karin, Kashofer, Karl, Jahn, Stephan W., Bauernhofer, Thomas, Pichler, Martin, Stöger, Herbert, Berghold, Andrea, Hoefler, Gerald, Speicher, Michael R., Heitzer, Ellen, Gerger, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923987/
https://www.ncbi.nlm.nih.gov/pubmed/33717225
http://dx.doi.org/10.1177/1758835920987658

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