Pharmacodynamic Drug–Drug Interaction on Human Peripheral Blood Mononuclear Cells Between Everolimus and Tacrolimus at the Therapeutic Concentration Range in Renal Transplantation

BACKGROUND: Everolimus (EVL) plus tacrolimus (TAC) therapy is effective and safe in renal transplantation. However, the pharmacokinetic and pharmacodynamic information for EVL combined with TAC is limited. We investigated the pharmacodynamic drug–drug interaction between EVL and TAC at their therape...

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Detalles Bibliográficos
Autores principales: Okihara, Masaaki, Takeuchi, Hironori, Akiyama, Shinichi, Yoshinaga, Reichi, Osato, Sayuri, Akashi, Isao, Kihara, Yu, Konno, Osamu, Iwamoto, Hitoshi, Oda, Takashi, Tanaka, Sachiko, Unezaki, Sakae, Hirano, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924008/
https://www.ncbi.nlm.nih.gov/pubmed/33633104
http://dx.doi.org/10.12659/AOT.928817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924008/
https://www.ncbi.nlm.nih.gov/pubmed/33633104
http://dx.doi.org/10.12659/AOT.928817

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