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Upregulation of COX4-2 via HIF-1α in Mitochondrial COX4-1 Deficiency

Cytochrome-c-oxidase (COX) subunit 4 (COX4) plays important roles in the function, assembly and regulation of COX (mitochondrial respiratory complex 4), the terminal electron acceptor of the oxidative phosphorylation (OXPHOS) system. The principal COX4 isoform, COX4-1, is expressed in all tissues, w...

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Detalles Bibliográficos
Autores principales: Douiev, Liza, Miller, Chaya, Ruppo, Shmuel, Benyamini, Hadar, Abu-Libdeh, Bassam, Saada, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924049/
https://www.ncbi.nlm.nih.gov/pubmed/33672589
http://dx.doi.org/10.3390/cells10020452