Encapsulating Halofuginone Hydrobromide in TPGS Polymeric Micelles Enhances Efficacy Against Triple-Negative Breast Cancer Cells

BACKGROUND: Halofuginone hydrobromide (HF) is a synthetic analogue of the naturally occurring quinazolinone alkaloid febrifugine, which has potential therapeutic effects against breast cancer, however, its poor water solubility greatly limits its pharmaceutical application. D-α-tocopherol polyethyle...

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Detalles Bibliográficos
Autores principales: Zuo, Runan, Zhang, Jingjing, Song, Xinhao, Hu, Shiheng, Gao, Xiuge, Wang, Junqi, Ji, Hui, Ji, Chunlei, Peng, Lin, Si, Hongbin, Li, Gonghe, Fang, Kun, Zhang, Junren, Jiang, Shanxiang, Guo, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924253/
https://www.ncbi.nlm.nih.gov/pubmed/33664573
http://dx.doi.org/10.2147/IJN.S289096

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