Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.

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Complement activation has been implicated in the pathogenesis of severe SARS-CoV-2 infection. However, it remains to be determined whether increased complement activation is a broad indicator of critical illness (and thus, no different in COVID-19). It is also unclear which pathways are contributing...

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Detalles Bibliográficos
Autores principales: Ma, Lina, Sahu, Sanjaya K., Cano, Marlene, Kuppuswamy, Vasanthan, Bajwa, Jamal, McPhatter, Ja’Nia, Pine, Alexander, Meizlish, Matthew, Goshua, George, Chang, C-Hong, Zhang, Hanming, Price, Christina, Bahel, Parveen, Rinder, Henry, Lei, Tingting, Day, Aaron, Reynolds, Daniel, Wu, Xiaobo, Schriefer, Rebecca, Rauseo, Adriana M., Goss, Charles W., O’Halloran, Jane A., Presti, Rachel M., Kim, Alfred H., Gelman, Andrew E., Cruz, Charles Dela, Lee, Alfred I., Mudd, Phillip, Chun, Hyung J., Atkinson, John P., Kulkarni, Hrishikesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924264/
https://www.ncbi.nlm.nih.gov/pubmed/33655244
http://dx.doi.org/10.1101/2021.02.22.432177
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