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Role of Shear Stress and tPA Concentration in the Fibrinolytic Potential of Thrombi

The resolution of arterial thrombi is critically dependent on the endogenous fibrinolytic system. Using well-established and complementary whole blood models, we investigated the endogenous fibrinolytic potential of the tissue-type plasminogen activator (tPA) and the intra-thrombus distribution of f...

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Detalles Bibliográficos
Autores principales: Whyte, Claire S., Mostefai, Hadj Ahmed., Baeten, Kim M., Lucking, Andrew J., Newby, David E., Booth, Nuala A., Mutch, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924342/
https://www.ncbi.nlm.nih.gov/pubmed/33672724
http://dx.doi.org/10.3390/ijms22042115