Lysophosphatidic Acid-Activated Calcium Signaling Is Elevated in Red Cells from Sickle Cell Disease Patients

(1) Background: It is known that sickle cells contain a higher amount of Ca(2+) compared to healthy red blood cells (RBCs). The increased Ca(2+) is associated with the most severe symptom of sickle cell disease (SCD), the vaso-occlusive crisis (VOC). The Ca(2+) entry pathway received the name of P(s...

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Autores principales: Wang, Jue, Hertz, Laura, Ruppenthal, Sandra, El Nemer, Wassim, Connes, Philippe, Goede, Jeroen S., Bogdanova, Anna, Birnbaumer, Lutz, Kaestner, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924404/
https://www.ncbi.nlm.nih.gov/pubmed/33672679
http://dx.doi.org/10.3390/cells10020456

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