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An Overview of Next-Generation Androgen Receptor-Targeted Therapeutics in Development for the Treatment of Prostate Cancer

Traditional endocrine therapy for prostate cancer (PCa) has been directed at suppression of the androgen receptor (AR) signaling axis since Huggins et al. discovered that diethylstilbestrol (DES; an estrogen) produced chemical castration and PCa tumor regression. Androgen deprivation therapy (ADT) s...

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Detalles Bibliográficos
Autores principales:	Mohler, Michael L., Sikdar, Arunima, Ponnusamy, Suriyan, Hwang, Dong-Jin, He, Yali, Miller, Duane D., Narayanan, Ramesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924596/ https://www.ncbi.nlm.nih.gov/pubmed/33672769 http://dx.doi.org/10.3390/ijms22042124

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