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Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice
Altered lipid metabolic pathways including hydrolysis of triglycerides are key players in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Whether adiponutrin (patatin-like phospholipase domain containing protein-3—PNPLA3) and monoacylglycerol lipase (MGL) synergistically contribute to...
Autores principales: | Tardelli, Matteo, Bruschi, Francesca V., Fuchs, Claudia D., Claudel, Thierry, Auer, Nicole, Kunczer, Victoria, Ronda, Onne A. H. O., Verkade, Henkjan J., Stojakovic, Tatjana, Scharnagl, Hubert, Trauner, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924608/ https://www.ncbi.nlm.nih.gov/pubmed/33672787 http://dx.doi.org/10.3390/ijms22042126 |
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