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RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms
BACKGROUND: Owing to the rapid advances in DNA sequencing technologies, whole genome from more and more species are becoming available at increasing pace. For whole-genome analysis, idiograms provide a very popular, intuitive and effective way to map and visualize the genome-wide information, such a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924719/ https://www.ncbi.nlm.nih.gov/pubmed/33816903 http://dx.doi.org/10.7717/peerj-cs.251 |
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author | Hao, Zhaodong Lv, Dekang Ge, Ying Shi, Jisen Weijers, Dolf Yu, Guangchuang Chen, Jinhui |
author_facet | Hao, Zhaodong Lv, Dekang Ge, Ying Shi, Jisen Weijers, Dolf Yu, Guangchuang Chen, Jinhui |
author_sort | Hao, Zhaodong |
collection | PubMed |
description | BACKGROUND: Owing to the rapid advances in DNA sequencing technologies, whole genome from more and more species are becoming available at increasing pace. For whole-genome analysis, idiograms provide a very popular, intuitive and effective way to map and visualize the genome-wide information, such as GC content, gene and repeat density, DNA methylation distribution, genomic synteny, etc. However, most available software programs and web servers are available only for a few model species, such as human, mouse and fly, or have limited application scenarios. As more and more non-model species are sequenced with chromosome-level assembly being available, tools that can generate idiograms for a broad range of species and be capable of visualizing more data types are needed to help better understanding fundamental genome characteristics. RESULTS: The R package RIdeogram allows users to build high-quality idiograms of any species of interest. It can map continuous and discrete genome-wide data on the idiograms and visualize them in a heat map and track labels, respectively. CONCLUSION: The visualization of genome-wide data mapping and comparison allow users to quickly establish a clear impression of the chromosomal distribution pattern, thus making RIdeogram a useful tool for any researchers working with omics. |
format | Online Article Text |
id | pubmed-7924719 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79247192021-04-02 RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms Hao, Zhaodong Lv, Dekang Ge, Ying Shi, Jisen Weijers, Dolf Yu, Guangchuang Chen, Jinhui PeerJ Comput Sci Bioinformatics BACKGROUND: Owing to the rapid advances in DNA sequencing technologies, whole genome from more and more species are becoming available at increasing pace. For whole-genome analysis, idiograms provide a very popular, intuitive and effective way to map and visualize the genome-wide information, such as GC content, gene and repeat density, DNA methylation distribution, genomic synteny, etc. However, most available software programs and web servers are available only for a few model species, such as human, mouse and fly, or have limited application scenarios. As more and more non-model species are sequenced with chromosome-level assembly being available, tools that can generate idiograms for a broad range of species and be capable of visualizing more data types are needed to help better understanding fundamental genome characteristics. RESULTS: The R package RIdeogram allows users to build high-quality idiograms of any species of interest. It can map continuous and discrete genome-wide data on the idiograms and visualize them in a heat map and track labels, respectively. CONCLUSION: The visualization of genome-wide data mapping and comparison allow users to quickly establish a clear impression of the chromosomal distribution pattern, thus making RIdeogram a useful tool for any researchers working with omics. PeerJ Inc. 2020-01-20 /pmc/articles/PMC7924719/ /pubmed/33816903 http://dx.doi.org/10.7717/peerj-cs.251 Text en ©2020 Hao et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Computer Science) and either DOI or URL of the article must be cited. |
spellingShingle | Bioinformatics Hao, Zhaodong Lv, Dekang Ge, Ying Shi, Jisen Weijers, Dolf Yu, Guangchuang Chen, Jinhui RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms |
title | RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms |
title_full | RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms |
title_fullStr | RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms |
title_full_unstemmed | RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms |
title_short | RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms |
title_sort | rideogram: drawing svg graphics to visualize and map genome-wide data on the idiograms |
topic | Bioinformatics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924719/ https://www.ncbi.nlm.nih.gov/pubmed/33816903 http://dx.doi.org/10.7717/peerj-cs.251 |
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