Cargando…

Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up

This retrospective cohort study was done to investigate the incidence of hypertension and its relation to the fasting blood glucose level in Korea. The eligible non-hypertensive subjects (n = 3,396,187) among the National Health Insurance Service-National Health Screening (NHIS-HEALS) examinees (n =...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahn, Soon-Ki, Lee, Ju-Mi, Ji, Seon Mi, Kim, Kyoung Hoon, Park, Jong-Heon, Hyun, Min Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924835/
https://www.ncbi.nlm.nih.gov/pubmed/33669927
http://dx.doi.org/10.3390/ijerph18042085
_version_ 1783659174438109184
author Ahn, Soon-Ki
Lee, Ju-Mi
Ji, Seon Mi
Kim, Kyoung Hoon
Park, Jong-Heon
Hyun, Min Kyung
author_facet Ahn, Soon-Ki
Lee, Ju-Mi
Ji, Seon Mi
Kim, Kyoung Hoon
Park, Jong-Heon
Hyun, Min Kyung
author_sort Ahn, Soon-Ki
collection PubMed
description This retrospective cohort study was done to investigate the incidence of hypertension and its relation to the fasting blood glucose level in Korea. The eligible non-hypertensive subjects (n = 3,396,187) among the National Health Insurance Service-National Health Screening (NHIS-HEALS) examinees (n = 10,644,911) in 2009 were followed up until 2015. A Cox proportional hazards regression was used to estimate the risk of the high blood glucose level for the incident hypertension while controlling for covariates’ confounding effect. The cumulative incidence rate was 10.6% for seven years (11.6% in men and 8.3% in women). The incidence density was 1474.8 per 100,000 person-years. High fasting blood glucose (adjusted Hazard Ratio (aHR), 1.836; 95% confidence interval (CI), 1.810 to 1.862), prediabetes (aHR, 1.249; 95% CI, 1.237 to 1.260), a history of diabetes mellitus (aHR, 1.635; 95% CI, 1.605 to 1.666), high triglyceride (aHR, 1.292; 95% CI, 1.280 to 1.303), a history of dyslipidemia (aHR, 1.279; 95% CI, 1.253 to 1.305) and prehypertension group (aHR, 1.964; 95% CI, 1.948 to 1.979) were significantly related to the incident hypertension after adjusting for covariates. Among real-world data in Korea, high blood glucose level was the independent risk factor for developing hypertension.
format Online
Article
Text
id pubmed-7924835
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-79248352021-03-03 Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up Ahn, Soon-Ki Lee, Ju-Mi Ji, Seon Mi Kim, Kyoung Hoon Park, Jong-Heon Hyun, Min Kyung Int J Environ Res Public Health Article This retrospective cohort study was done to investigate the incidence of hypertension and its relation to the fasting blood glucose level in Korea. The eligible non-hypertensive subjects (n = 3,396,187) among the National Health Insurance Service-National Health Screening (NHIS-HEALS) examinees (n = 10,644,911) in 2009 were followed up until 2015. A Cox proportional hazards regression was used to estimate the risk of the high blood glucose level for the incident hypertension while controlling for covariates’ confounding effect. The cumulative incidence rate was 10.6% for seven years (11.6% in men and 8.3% in women). The incidence density was 1474.8 per 100,000 person-years. High fasting blood glucose (adjusted Hazard Ratio (aHR), 1.836; 95% confidence interval (CI), 1.810 to 1.862), prediabetes (aHR, 1.249; 95% CI, 1.237 to 1.260), a history of diabetes mellitus (aHR, 1.635; 95% CI, 1.605 to 1.666), high triglyceride (aHR, 1.292; 95% CI, 1.280 to 1.303), a history of dyslipidemia (aHR, 1.279; 95% CI, 1.253 to 1.305) and prehypertension group (aHR, 1.964; 95% CI, 1.948 to 1.979) were significantly related to the incident hypertension after adjusting for covariates. Among real-world data in Korea, high blood glucose level was the independent risk factor for developing hypertension. MDPI 2021-02-21 2021-02 /pmc/articles/PMC7924835/ /pubmed/33669927 http://dx.doi.org/10.3390/ijerph18042085 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ahn, Soon-Ki
Lee, Ju-Mi
Ji, Seon Mi
Kim, Kyoung Hoon
Park, Jong-Heon
Hyun, Min Kyung
Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up
title Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up
title_full Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up
title_fullStr Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up
title_full_unstemmed Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up
title_short Incidence Hypertension and Fasting Blood Glucose from Real-World Data: Retrospective Cohort for 7-Years Follow-Up
title_sort incidence hypertension and fasting blood glucose from real-world data: retrospective cohort for 7-years follow-up
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924835/
https://www.ncbi.nlm.nih.gov/pubmed/33669927
http://dx.doi.org/10.3390/ijerph18042085
work_keys_str_mv AT ahnsoonki incidencehypertensionandfastingbloodglucosefromrealworlddataretrospectivecohortfor7yearsfollowup
AT leejumi incidencehypertensionandfastingbloodglucosefromrealworlddataretrospectivecohortfor7yearsfollowup
AT jiseonmi incidencehypertensionandfastingbloodglucosefromrealworlddataretrospectivecohortfor7yearsfollowup
AT kimkyounghoon incidencehypertensionandfastingbloodglucosefromrealworlddataretrospectivecohortfor7yearsfollowup
AT parkjongheon incidencehypertensionandfastingbloodglucosefromrealworlddataretrospectivecohortfor7yearsfollowup
AT hyunminkyung incidencehypertensionandfastingbloodglucosefromrealworlddataretrospectivecohortfor7yearsfollowup