Cargando…
Estrogen receptor alpha in the brain mediates tamoxifen-induced changes in physiology in mice
Adjuvant tamoxifen therapy improves survival in breast cancer patients. Unfortunately, long-term treatment comes with side effects that impact health and quality of life, including hot flashes, changes in bone density, and fatigue. Partly due to a lack of proven animal models, the tissues and cells...
Autores principales: | Zhang, Zhi, Park, Jae Whan, Ahn, In Sook, Diamante, Graciel, Sivakumar, Nilla, Arneson, Douglas, Yang, Xia, van Veen, J Edward, Correa, Stephanie M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924955/ https://www.ncbi.nlm.nih.gov/pubmed/33647234 http://dx.doi.org/10.7554/eLife.63333 |
Ejemplares similares
-
FOXC1 is associated with estrogen receptor alpha and affects sensitivity of tamoxifen treatment in breast cancer
por: Wang, Jinhua, et al.
Publicado: (2016) -
Systems spatiotemporal dynamics of traumatic brain injury at single-cell resolution reveals humanin as a therapeutic target
por: Arneson, Douglas, et al.
Publicado: (2022) -
ScRNA-seq Reveals a Role of Mammary Luminal Epithelium in Adipocyte Adaptations
por: Santos, Luis, et al.
Publicado: (2021) -
Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes
por: Rajbhandari, Prashant, et al.
Publicado: (2019) -
Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers
por: Raj, Ganesh V, et al.
Publicado: (2017)