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Mechanistic insights into KDM4A driven genomic instability

Alterations in global epigenetic signatures on chromatin are well established to contribute to tumor initiation and progression. Chromatin methylation status modulates several key cellular processes that maintain the integrity of the genome. KDM4A, a demethylase that belongs to the Fe-II dependent d...

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Detalles Bibliográficos
Autores principales: Young, Nicolas L., Dere, Ruhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925003/
https://www.ncbi.nlm.nih.gov/pubmed/33492339
http://dx.doi.org/10.1042/BST20191219