Cargando…
Mechanistic insights into KDM4A driven genomic instability
Alterations in global epigenetic signatures on chromatin are well established to contribute to tumor initiation and progression. Chromatin methylation status modulates several key cellular processes that maintain the integrity of the genome. KDM4A, a demethylase that belongs to the Fe-II dependent d...
Autores principales: | Young, Nicolas L., Dere, Ruhee |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925003/ https://www.ncbi.nlm.nih.gov/pubmed/33492339 http://dx.doi.org/10.1042/BST20191219 |
Ejemplares similares
-
Advances in mechanisms of genetic instability related to hereditary neurological diseases
por: Wells, Robert D., et al.
Publicado: (2005) -
Chromosomal Instability in Chronic Myeloid Leukemia: Mechanistic Insights and Effects
por: Senapati, Jayastu, et al.
Publicado: (2022) -
The Use of Murine Models for Studying Mechanistic Insights of Genomic Instability in Multiple Myeloma
por: Vlummens, Philip, et al.
Publicado: (2019) -
Mechanistic Insight into the Effects of Curcumin on Neuroinflammation-Driven Chronic Pain
por: Hasriadi,, et al.
Publicado: (2021) -
Mechanistic and structural studies of KDM‐catalysed demethylation of histone 1 isotype 4 at lysine 26
por: Walport, Louise J., et al.
Publicado: (2018)