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The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective

Toxic epidermal necrolysis (TEN) is a dermatological emergency that is often associated with high mortality. It is differentiated from Stevens-Johnson syndrome (SJS) based on the percentage of the total body surface area affected. There has been an established correlation with certain medications th...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Shaikh, Ali Raza, Yoon, Thomas, Shah, Shreeja, Mahoney, James W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925054/
https://www.ncbi.nlm.nih.gov/pubmed/33680588
http://dx.doi.org/10.7759/cureus.13042
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author Zhang, Qian
Shaikh, Ali Raza
Yoon, Thomas
Shah, Shreeja
Mahoney, James W
author_facet Zhang, Qian
Shaikh, Ali Raza
Yoon, Thomas
Shah, Shreeja
Mahoney, James W
author_sort Zhang, Qian
collection PubMed
description Toxic epidermal necrolysis (TEN) is a dermatological emergency that is often associated with high mortality. It is differentiated from Stevens-Johnson syndrome (SJS) based on the percentage of the total body surface area affected. There has been an established correlation with certain medications that could trigger the development of such a devastating disease. Despite numerous research studies conducted on aspects of this disease entity, TEN remains foreign to many general Internists situated in a community setting due to the extremely low disease prevalence that leads to a lack of overall experience and medical resources in dealing with this medical condition. Thus, we outlined several important management aspects of TEN/SJS that an Internist should be aware of in order to assist in prompt clinical decision making and prognosis forecasting as well as deliver effective family communication. 
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spelling pubmed-79250542021-03-04 The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective Zhang, Qian Shaikh, Ali Raza Yoon, Thomas Shah, Shreeja Mahoney, James W Cureus Internal Medicine Toxic epidermal necrolysis (TEN) is a dermatological emergency that is often associated with high mortality. It is differentiated from Stevens-Johnson syndrome (SJS) based on the percentage of the total body surface area affected. There has been an established correlation with certain medications that could trigger the development of such a devastating disease. Despite numerous research studies conducted on aspects of this disease entity, TEN remains foreign to many general Internists situated in a community setting due to the extremely low disease prevalence that leads to a lack of overall experience and medical resources in dealing with this medical condition. Thus, we outlined several important management aspects of TEN/SJS that an Internist should be aware of in order to assist in prompt clinical decision making and prognosis forecasting as well as deliver effective family communication.  Cureus 2021-01-31 /pmc/articles/PMC7925054/ /pubmed/33680588 http://dx.doi.org/10.7759/cureus.13042 Text en Copyright © 2021, Zhang et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Zhang, Qian
Shaikh, Ali Raza
Yoon, Thomas
Shah, Shreeja
Mahoney, James W
The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective
title The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective
title_full The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective
title_fullStr The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective
title_full_unstemmed The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective
title_short The Reflection on the Management of Toxic Epidermal Necrolysis in the Community Setting: An Internist's Perspective
title_sort reflection on the management of toxic epidermal necrolysis in the community setting: an internist's perspective
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925054/
https://www.ncbi.nlm.nih.gov/pubmed/33680588
http://dx.doi.org/10.7759/cureus.13042
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