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Anabolic Steroid-Induced Myocardial Infarction in a Young Male

Misuse of androgenic-anabolic steroids (AAS) has been well known to increase the risk for a cardiac problem, including acute myocardial infarction (MI). Steroids once thought a magic drug providing immediate relief to patients, also have a darker aspect of its severe side effects. AAS are widely use...

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Detalles Bibliográficos
Autores principales: Samreen, Fnu, Popal, Ubaidullah, Qutrio Baloch, Zulfiqar A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925058/
https://www.ncbi.nlm.nih.gov/pubmed/33680596
http://dx.doi.org/10.7759/cureus.13054
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author Samreen, Fnu
Popal, Ubaidullah
Qutrio Baloch, Zulfiqar A
author_facet Samreen, Fnu
Popal, Ubaidullah
Qutrio Baloch, Zulfiqar A
author_sort Samreen, Fnu
collection PubMed
description Misuse of androgenic-anabolic steroids (AAS) has been well known to increase the risk for a cardiac problem, including acute myocardial infarction (MI). Steroids once thought a magic drug providing immediate relief to patients, also have a darker aspect of its severe side effects. AAS are widely used these days, especially in teenagers, bodybuilders, and athletes. MI is thought to be a disease of old age, but young patients with MI without risk factors draw attention to the possibility of drugs such as cocaine, AAS abuse, and amphetamine.  In this article, we report the case of a 38-year-old African-American male, with a history of AAS abuse, who arrived at the emergency department with complaints of severe chest pain radiating to the left arm. An electrocardiogram (ECG) revealed ST-elevation MI (STEMI) and elevated troponin. The patient was transferred to the cardiac catheterization lab for an emergent catheterization which showed 100% stenosis of the left anterior descending artery and a drug-eluting stent was placed. An echocardiogram showed an ejection fraction of 35%. All blood workup was negative. The patient was discharged on aspirin, ticagrelor, statin, ACE inhibitor, and B-blocker after three days. Chest pain in a young patient population secondary to MI is not uncommon these days and the most important thing to evaluate is drug history, including AAS use. Athletes, bodybuilders, and others who use steroids or other drugs that are responsible for MI should be under the supervision of physicians so that the complications of steroids are ascertained, and if steroids are needed for any medical illness, proper dosage and follow-up should be emphasized. Therefore, while taking history from a patient, it is essential for physicians to be aware of this association of steroids with coronary artery disease.
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spelling pubmed-79250582021-03-04 Anabolic Steroid-Induced Myocardial Infarction in a Young Male Samreen, Fnu Popal, Ubaidullah Qutrio Baloch, Zulfiqar A Cureus Cardiology Misuse of androgenic-anabolic steroids (AAS) has been well known to increase the risk for a cardiac problem, including acute myocardial infarction (MI). Steroids once thought a magic drug providing immediate relief to patients, also have a darker aspect of its severe side effects. AAS are widely used these days, especially in teenagers, bodybuilders, and athletes. MI is thought to be a disease of old age, but young patients with MI without risk factors draw attention to the possibility of drugs such as cocaine, AAS abuse, and amphetamine.  In this article, we report the case of a 38-year-old African-American male, with a history of AAS abuse, who arrived at the emergency department with complaints of severe chest pain radiating to the left arm. An electrocardiogram (ECG) revealed ST-elevation MI (STEMI) and elevated troponin. The patient was transferred to the cardiac catheterization lab for an emergent catheterization which showed 100% stenosis of the left anterior descending artery and a drug-eluting stent was placed. An echocardiogram showed an ejection fraction of 35%. All blood workup was negative. The patient was discharged on aspirin, ticagrelor, statin, ACE inhibitor, and B-blocker after three days. Chest pain in a young patient population secondary to MI is not uncommon these days and the most important thing to evaluate is drug history, including AAS use. Athletes, bodybuilders, and others who use steroids or other drugs that are responsible for MI should be under the supervision of physicians so that the complications of steroids are ascertained, and if steroids are needed for any medical illness, proper dosage and follow-up should be emphasized. Therefore, while taking history from a patient, it is essential for physicians to be aware of this association of steroids with coronary artery disease. Cureus 2021-02-01 /pmc/articles/PMC7925058/ /pubmed/33680596 http://dx.doi.org/10.7759/cureus.13054 Text en Copyright © 2021, Samreen et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Samreen, Fnu
Popal, Ubaidullah
Qutrio Baloch, Zulfiqar A
Anabolic Steroid-Induced Myocardial Infarction in a Young Male
title Anabolic Steroid-Induced Myocardial Infarction in a Young Male
title_full Anabolic Steroid-Induced Myocardial Infarction in a Young Male
title_fullStr Anabolic Steroid-Induced Myocardial Infarction in a Young Male
title_full_unstemmed Anabolic Steroid-Induced Myocardial Infarction in a Young Male
title_short Anabolic Steroid-Induced Myocardial Infarction in a Young Male
title_sort anabolic steroid-induced myocardial infarction in a young male
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925058/
https://www.ncbi.nlm.nih.gov/pubmed/33680596
http://dx.doi.org/10.7759/cureus.13054
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