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Clostridioides difficile para-Cresol Production Is Induced by the Precursor para-Hydroxyphenylacetate
Clostridioides difficile is an etiological agent for antibiotic-associated diarrheal disease. C. difficile produces a phenolic compound, para-cresol, which selectively targets gammaproteobacteria in the gut, facilitating dysbiosis. C. difficile decarboxylates para-hydroxyphenylacetate (p-HPA) to pro...
Autores principales: | Harrison, Mark A., Faulds-Pain, Alexandra, Kaur, Harparkash, Dupuy, Bruno, Henriques, Adriano O., Martin-Verstraete, Isabelle, Wren, Brendan W., Dawson, Lisa F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925072/ https://www.ncbi.nlm.nih.gov/pubmed/32631945 http://dx.doi.org/10.1128/JB.00282-20 |
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