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TRAF6 and TAK1 Contribute to SAMHD1-Mediated Negative Regulation of NF-κB Signaling

Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) restricts HIV-1 replication by limiting the intracellular deoxynucleoside triphosphate (dNTP) pool. SAMHD1 also suppresses the activation of NF-κB in response to viral infections and inflammatory stimuli. However, the mechanisms by whic...

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Detalles Bibliográficos
Autores principales:	Espada, Constanza E., St. Gelais, Corine, Bonifati, Serena, Maksimova, Victoria V., Cahill, Michael P., Kim, Sun Hee, Wu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925110/ https://www.ncbi.nlm.nih.gov/pubmed/33177202 http://dx.doi.org/10.1128/JVI.01970-20

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