Cardiac Rehabilitation With Dynamic Exercise Increases the Number of Muse Cells in the Peripheral Blood of Patients With Heart Disease

Background: It is still unclear whether dynamic exercise increases the number of Muse cells, pluripotent stem cells, in the peripheral blood. Methods and Results: The number of Muse cells, SSEA3(+) and CD105(+) double-positive cells, in the peripheral blood was measured using FACS before and after 4...

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Detalles Bibliográficos
Autores principales: Minatoguchi, Shingo, Ando, Takahiro, Tanaka, Toshiki, Yamada, Yoshihisa, Kanamori, Hiromitsu, Kawasaki, Masanori, Nishigaki, Kazuhiko, Minatoguchi, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Circulation Society 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7925125/
https://www.ncbi.nlm.nih.gov/pubmed/33693070
http://dx.doi.org/10.1253/circrep.CR-18-0003
Descripción
Sumario:Background: It is still unclear whether dynamic exercise increases the number of Muse cells, pluripotent stem cells, in the peripheral blood. Methods and Results: The number of Muse cells, SSEA3(+) and CD105(+) double-positive cells, in the peripheral blood was measured using FACS before and after 40 min of cardiac rehabilitation with dynamic exercise in 6 patients with heart disease. The number of Muse cells significantly increased after cardiac rehabilitation in all patients. Muse cell mobilization may be related to the beneficial clinical outcome of cardiac rehabilitation. Conclusions: Cardiac rehabilitation increases the number of Muse cells in the peripheral blood.

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